DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33233 and Svop

DIOPT Version :9

Sequence 1:	NP_995978.2	Gene:	CG33233 / 2769005	FlyBaseID:	FBgn0053233	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_081081.1	Gene:	Svop / 68666	MGIID:	1915916	Length:	548	Species:	Mus musculus

Alignment Length:	496	Identity:	105/496 - (21%)
Similarity:	198/496 - (39%)	Gaps:	73/496 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VDTALLTIGYGLGQVIIFMVSFFIYMYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSLLGGMV 70
            |:.|:..||:|..|..:.:::...:|....|.|....|.....||:.....:..||.:.:..||:
Mouse    70 VEDAVEAIGFGRFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMM 134

  Fly    71 ASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYS-LSVIRIIVGTFLSAVASLQVGFL 134
            :|....|.::|:||||..::::::..|.:.::||..| :|| :.|:|.:||..:..|.. .|...
Mouse   135 SSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAP-VYSWILVLRGLVGFGIGGVPQ-SVTLY 197

  Fly   135 GEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFLMMFFMIPGWL 199
            .||..:|.|...:.:......:..::..|:|:.::|:            ..||:|::....|..|
Mouse   198 AEFLPMKARAKCILLIEVFWAIGTVFEVLLAVFVMPS------------LGWRWLLLLSAAPLLL 250

  Fly   200 ALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRKKWE--DVDITLSEEKSSTNDQEGFWKTV 262
            ..|....:||:..:.:.....:||:..||.|...|.....  .:.|:..|::....|
Mouse   251 FAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRD-------- 307

  Fly   263 WYEYKLLFSKPHVFKFFICL--FLIFGIFFTSIGLGIWFPVIRNMDNSGSNRLCDLVNNNPTFIN 325
                  ||: || |::...|  |:.|...|:..||     |:...:...:..:|.:.:.....
Mouse   308 ------LFT-PH-FRWTTLLLWFIWFSNAFSYYGL-----VLLTTELFQAGDVCSISSRKKAV-- 357

  Fly   326 HEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYIGCFILASVLVH-W----MTRKYVIALHILIS 385
             ||           ||:.....|....|....:........|||. |    :.||..:||..:|.
Mouse   358 -EA-----------KCSLACEYLSKEDYMDLLWTTLSEFPGVLVTLWVIDRLGRKKTMALCFIIF 410

  Fly   386 MILGISLNI-MKQPTVVLIFFVLMMVLPG------VLIPLATSVLVDCLPVNLRGKALCMVRSLA 443
            .:..:.|.| :.:..:.|:.|:....:.|      |..|       :..|...|...|.....:|
Mouse   411 SLCSLLLFICIGRNVLTLLLFIARAFISGGFQAAYVYTP-------EVYPTATRALGLGTCSGMA 468

  Fly   444 RFGGVLGSTMIGLFIRVTCDVTFNIFNLCLAICVVLAVFQP 484
            |.|.::...:..:.:..:..:|..:::.|..:..|.:.|.|
Mouse   469 RVGALITPFIAQVMLESSVYLTLAVYSGCCLLAGVASCFLP 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	94/445 (21%)
		MFS	23..>208	CDD:119392	42/185 (23%)
		MFS	354..>482	CDD:304372	25/139 (18%)
Svop	NP_081081.1	2A0119	9..519	CDD:273328	105/496 (21%)
Svop	NP_081081.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	521..548
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910