Protein Alignment CG33233 and SLC22A5

DIOPT Version :9

• Sequence 1: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001295051.1
• Gene: SLC22A5 / 6584
• HGNCID: 10969
• Length: 581
• Species: Homo sapiens
• Alignment Length: 487
• Identity: 98/487 - (20%)
• Similarity: 180/487 - (36%)
• Gaps: 153/487 - (31%)

  Fly    49 CEFDTSPKEKTLLANSLLGGMVASGLFI-GFLADRYGRKFVIRLALVGALSFSVISALMPDLYSL 112
            ||.|.    |..|..||....|..|.|| |.|:||:|||.|:.:.:.....||.:.....:....
Human   160 CEDDW----KAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMF 220

  Fly   113 SVIRIIV--GTFLSAVASLQVG--FLGEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNF 173
            .|:.::|  |...:.||:..:|  .||:         :|.|...:.|:.:.|.  ....:||
Human   221 VVLFVLVGMGQISNYVAAFVLGTEILGK---------SVRIIFSTLGVCIFYA--FGYMVLP--- 271

  Fly   174 NVDLSSSYNLRVWRFLMMFFMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMN---- 234
                ..:|.:|.||.|::...:||.|.:.....:||:|.:|:|..|.::|.:.::...:.|
Human   272 ----LFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVV 332

  Fly   235 ------RKKWEDVDITLSEEKSSTNDQEGFWKTVWYEYKLLFSKPHVFKFFICLFLIFGIFFTSI 293
                  ..:.:|    ||.:|..:::.....:|  :..:::    .:....:.:.:..|.|
Human   333 PSTIFDPSELQD----LSSKKQQSHNILDLLRT--WNIRMV----TIMSIMLWMTISVGYF---- 383

  Fly   294 GLGIWFPVIRNMDNSGSNRLCDLVNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTY 358
            ||.:                                ||                   |..:|..:
Human   384 GLSL--------------------------------DT-------------------PNLHGDIF 397

  Fly   359 IGCF----------ILASVLVHWMTRKYVIALHILISMILGISLNIMKQPTVVLIFFVLMMVLPG 413
            :.||          :||.:|:.::.|:|.:|    .::.||.|         ||:|   |.::|.
Human   398 VNCFLSAMVEVPAYVLAWLLLQYLPRRYSMA----TALFLGGS---------VLLF---MQLVPP 446

  Fly   414 VLIPLATSVLV-------------------DCLPVNLRGKALCMVRSLARFGGVLGS--TMIGLF 457
            .|..||| |||                   :..|..:|...:.:..:.:|.|.:|..  ..:|.:
Human   447 DLYYLAT-VLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAY 510

  Fly   458 IRVTCDVTFNIFNLCLAICVVLAVFQPKDIVT 489
            .|.   :.:.:......:..:|.:|.|:...|
Human   511 DRF---LPYILMGSLTILTAILTLFLPESFGT 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	92/445 (21%)
		MFS	23..>208	CDD:119392	43/163 (26%)
		MFS	354..>482	CDD:304372	32/158 (20%)
SLC22A5	NP_001295051.1	2A0119	12..544	CDD:273328	98/487 (20%)
		MFS	162..534	CDD:119392	94/478 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153364
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840