Protein Alignment CG33233 and SLC22A1

DIOPT Version :9

• Sequence 1: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_005267159.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 610
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 109/473 - (23%)
• Similarity: 189/473 - (39%)
• Gaps: 120/473 - (25%)

  Fly    28 FIYMYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSLLGGMVASGLFIGFLADRYGRKF-VIRL 91
            ::|....:..:|...||...|.:.|       |..:.|..|.:...|.:|:.|||:|||. ::..
Human   125 WVYDTPGSSIVTEFNLVCADSWKLD-------LFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGT 182

  Fly    92 ALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQVGF--LGEFHAIKWRPITVAICSQSQ 154
            .||.|:| .|:.|..|:..|:.:.|::.|  |.:..:...|:  :.||.....|. ||||..|
Human   183 VLVNAVS-GVLMAFSPNYMSMLLFRLLQG--LVSKGNWMAGYTLITEFVGSGSRR-TVAIMYQ-- 241

  Fly   155 GLALIYCPLVAMAILPNNFNVDLSS----SYNLRVWRFLMMFFMIPGWLALVGICLVPETPHFLM 215
                       ||     |.|.|.:    :|.|..||:|.:...:|.:|.|:....|||:|.:|:
Human   242 -----------MA-----FTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLL 290

  Fly   216 SVNRPDKALLALKWICRMNRK------KWEDVDITLSEEKSSTNDQEGFWKTVWYEYKLLFSKPH 274
            |..|..:|:..:..|.:.|.|      |...::..::|:.|.:             :..||..|.
Human   291 SQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPS-------------FADLFRTPR 342

  Fly   275 VFK-FFICLFLIFGIFFTSIGLGIWFPVIRNMDNSGSNRLCDLVNNNPTFINHEADDTNGTDSES 338
            :.| .||.::|             ||              .|.|......::..|  |:|
Human   343 LRKRTFILMYL-------------WF--------------TDSVLYQGLILHMGA--TSG----- 373

  Fly   339 PKCNDEMTNL-IDPVYYGFTYI-GCFILASVLVHWMTRKYVIALHILISMILGISLNIM--KQPT 399
                    || :|.:|.....| |.|| |.:.:..:.|.|.:|:.   :::.|.:..:|  ..|.
Human   374 --------NLYLDFLYSALVEIPGAFI-ALITIDRVGRIYPMAMS---NLLAGAACLVMIFISPD 426

  Fly   400 VVLIFFVLMMV-LPGVLIPLATSVLV--DCLPVNLRGKALCMVRSLARFGGVLGSTMIGLFIRVT 461
            :..:..::|.| ..|:.|.:....||  :..|..:|...:.:..||...||:           :|
Human   427 LHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGI-----------IT 480

  Fly   462 CDVTFNIFNLCLAICVVL 479
            ..:.|.:..:..|:.::|
Human   481 PFIVFRLREVWQALPLIL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	105/443 (24%)
		MFS	23..>208	CDD:119392	50/186 (27%)
		MFS	354..>482	CDD:304372	27/132 (20%)
SLC22A1	XP_005267159.1	2A0119	12..499	CDD:273328	109/473 (23%)
		MFS	118..484	CDD:119392	106/457 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153375
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840