DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33233 and sv2

DIOPT Version :9

Sequence 1:	NP_995978.2	Gene:	CG33233 / 2769005	FlyBaseID:	FBgn0053233	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	XP_009296040.1	Gene:	sv2 / 570651	ZFINID:	ZDB-GENE-000607-80	Length:	522	Species:	Danio rerio

Alignment Length:	507	Identity:	108/507 - (21%)
Similarity:	208/507 - (41%)	Gaps:	71/507 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DTALLTIGYGLGQVIIFMVSFFIYMYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSLLGGMVA 71
            :.|:...|:||...::.:|..:.......|.:...:|:....|:...|..:..:|..|:..||:.
Zfish    34 EEAVEKAGFGLFHWLLLVVCGWANASDAVEILCVSFLLPTARCDLQLSSADMGILTASIFLGMMV 98

  Fly    72 SGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQVGFLGE 136
            .|...||||||.||:.|:.::|....:|..:::|.|..:...::|...|..:.....:...:..|
Zfish    99 GGCVWGFLADRRGRRSVLVVSLAVNGTFGAVASLAPTFWLFLLLRFFSGVGVGGSIPVIFSYFSE 163

  Fly   137 FHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSY---NLRVWRFLMMFFMIPGW 198
            |.....|...::..:.......|....||..::|   ...|.:.:   :.:.||..::...||..
Zfish   164 FQPCLRRGAMISALATFWMAGNILAAGVAWLVIP---RTSLHADWGWLDFQSWRLFVVLCSIPSL 225

  Fly   199 -LALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRK-------------KWEDVDITLSEEK 249
             .||:....:||:|.|||...|..:||...:.|.::|.:             :.:|.::......
Zfish   226 SSALIFRLFMPESPKFLMEAGREMEALSVFQKIYKLNNRGATKPFPVSGLMIRPKDDEVKNRPSH 290

  Fly   250 SSTNDQE--GFWKTVWYEYKLLFSKPHVFKFFICLFLIFGIFFTSIGLGIWFP-VIRNMDNSGSN 311
            ||:..|.  ..........|.||.:|...:..:.:.:.|.|.|...||.:||| :.:..::.||.
Zfish   291 SSSRSQRFINQLTQALVPLKQLFVRPLASRSVVLVIIFFCISFGYYGLWMWFPELFKRAEDGGSP 355

  Fly   312 RLCDLVNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYIGCFILAS---------- 366
              |             |:.:...::|:.||....|.:         |:..||.|:
Zfish   356 --C-------------ANMSRAQNAENEKCYPVKTAV---------YMEGFITAASNLPGNIFTI 396

  Fly   367 VLVHWMTRKYVIALHILISMILGISLNIMKQPTVVLIFFVLMMVLPGVLIPLATSVL----VDCL 427
            :|:..:..|.::::.:|:|.:....:.::|..|..||   :..|..||.: ::.:.|    .:..
Zfish   397 LLMDRIGGKILLSVSLLVSGVSVFVIYVVKTKTQSLI---VSCVFSGVSV-ISWNALDVVGTELY 457

  Fly   428 PVNLRGKALCMVRSLARFGGVLGSTMIGLFIRVTCDVTFNIFNLCLAICVVL 479
            |..||..||.:...:.|...::|:.:.|..:..:|.|..      |.:||:|
Zfish   458 PTQLRSSALGVFTGVGRVAAIMGNVVFGQLVDSSCAVPL------LMVCVLL 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	96/462 (21%)
		MFS	23..>208	CDD:119392	39/188 (21%)
		MFS	354..>482	CDD:304372	30/140 (21%)
sv2	XP_009296040.1	2A0115	33..488	CDD:273327	102/484 (21%)
sv2	XP_009296040.1	MFS	50..500	CDD:119392	101/486 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920