DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33233 and si:dkey-119m7.4

DIOPT Version :9

Sequence 1:	NP_995978.2	Gene:	CG33233 / 2769005	FlyBaseID:	FBgn0053233	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_001038399.1	Gene:	si:dkey-119m7.4 / 560629	ZFINID:	ZDB-GENE-040724-70	Length:	413	Species:	Danio rerio

Alignment Length:	290	Identity:	74/290 - (25%)
Similarity:	131/290 - (45%)	Gaps:	36/290 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SVTESMTAGY------LVVLTSCEFDTSPKEKTL--LANSL-LGGMVASGLFIGFLADRYGRKFV 88
            |..:..|.|:      .:...:.|:|...:..|:  :.:|: :.|::...:..|.|||:|||:.:
Zfish    97 STAKGCTGGWEFSKEVFLSTIATEWDLVCENATMNNIGSSIYMFGLLVGAVLFGALADKYGRRII 161

  Fly    89 IRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQVGFLG-EFHAIKWRPITVAICSQ 152
            |.:.|.....|.|.:|..|:.|...::|.:|||.:|||. :....|| |:...|.|.:...|...
Zfish   162 ILIGLAIQAIFGVGAAFAPNFYIYVLLRFVVGTTVSAVI-MNAFVLGTEWTGPKKRMLAGVITDY 225

  Fly   153 SQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFLMMFFMIPGWLALVGICLVPETPHFLMSV 217
            ..|...|....||               |.:|.||.|.:....|.:|.|..:.::|::..:||:.
Zfish   226 FFGFGYILLAGVA---------------YLIRDWRKLQLAISAPSFLFLFYVWVLPKSARWLMAN 275

  Fly   218 NRPDKALLALKWICRMNRKKWEDVDITLSEE-KSSTNDQEGFWKTVWYEYKLLFSKPHVFKFFIC 281
            |:.::||..::....:|.|..||.|:.|.:. |||...||....||..    |...|.:.|..:.
Zfish   276 NKHEEALDLIRKAALINGKPLEDDDMELYQSPKSSEKLQEQRKYTVLD----LVRTPRMRKQSLI 336

  Fly   282 LFLIFGIFFTSIGLGIWFPVIRNMDNSGSN 311
            ||.::     .:.:.:::.:..|:.:.|.|
Zfish   337 LFYLW-----FVNVLVYYGLSLNISDFGMN 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	74/290 (26%)
		MFS	23..>208	CDD:119392	47/184 (26%)
		MFS	354..>482	CDD:304372
si:dkey-119m7.4	NP_001038399.1	2A0119	11..413	CDD:273328	74/290 (26%)
si:dkey-119m7.4	NP_001038399.1	MFS	112..>273	CDD:119392	45/176 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588516
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840