Protein Alignment CG33233 and SLC22A10

DIOPT Version :10

• Sequence 1: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001034841.3
• Gene: SLC22A10 / 387775
• HGNCID: 18057
• Length: 541
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 103/473 - (21%)
• Similarity: 178/473 - (37%)
• Gaps: 139/473 - (29%)

  Fly    49 CEFDTSPKEKTLLANSLLGGMVASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLS 113
            |::.:.   |:::...||.||:..|:..|.::||:||:|::|..|:........:|..|......
Human   139 CDYQSL---KSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCLLQLAITDTCAAFAPTFPVYC 200

  Fly   114 VIRIIVGTFLSAVASLQVGFLGEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLS 178
            |:|.:.|  .|::..:....|         |||..|...|:.|.:|                 ||
Human   201 VLRFLAG--FSSMIIISNNSL---------PITEWIRPNSKALVVI-----------------LS 237

  Fly   179 S-------------SYNLRVWRFL--------MMFFMIPGWLALVGICLVPETPHFLMSVNRPDK 222
            |             :|..|.|:.|        .:||::..||.        |:..:|:..|:.|:
Human   238 SGALSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLV--------ESARWLIITNKLDE 294

  Fly   223 ALLALKWICRMNRKKWEDVDITLSEEKSSTNDQEGF----WKTVWYEYKLLFSKPHVFKFFICLF 283
            .|.||:.:.|.|..|  :.:.||:.|...:..||..    .||...:   ||..|.:.| .||:
Human   295 GLKALRKVARTNGIK--NAEETLNIEVVRSTMQEELDAAQTKTTVCD---LFRNPSMRK-RICI- 352

  Fly   284 LIFGIFFTSIGLGIWFPVIRNMDNSGSN---------------RLCDLVNNNPTFINHEADDTNG 333
            |:|..|..:|.   ::..:.|:.:.|||               |...|:.     :||
Human   353 LVFLRFANTIP---FYGTMVNLQHVGSNIFLLQVLYGAVALIVRCLALLT-----LNH------- 402

  Fly   334 TDSESPKCNDEMTNLIDPVYYGFTYIGCFILASVLVHWMTRKYVIALHILISMILGISLNIMKQP 398
                       |...|..:.:.| .:|..|||:..|    .|.:..|.:.:: .|||..:.....
Human   403 -----------MGRRISQILFMF-LVGLSILANTFV----PKEMQTLRVALA-CLGIGCSAATFS 450

  Fly   399 TVVLIFFVLMMVLPGVLIPLATSVLVDCLPVNLRGKALCMVRSLARFGGVLGSTMIGL--FIRVT 461
            :|.:.|                   ::.:|..||.:|..:..:.:|.|..|...::.|  |....
Human   451 SVAVHF-------------------IELIPTVLRARASGIDLTASRIGAALAPLLMTLTVFFTTL 496

  Fly   462 CDVTFNIFNLCLAICVVL 479
            ..:.:.||.:...:.|.|
Human   497 PWIIYGIFPIIGGLIVFL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	2A0119	<49..>295	CDD:273328	67/270 (25%)
SLC22A10	NP_001034841.3	MFS_OAT	109..516	CDD:340932	103/473 (22%)