DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33233 and CG31272

DIOPT Version :9

Sequence 1:	NP_995978.2	Gene:	CG33233 / 2769005	FlyBaseID:	FBgn0053233	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	116/525 - (22%)
Similarity:	219/525 - (41%)	Gaps:	62/525 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DTALLTIGYGLGQVIIFMVSFFIYMYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSLLGGMVA 71
            |.|:...|:|:..:::.:||......::.||.:..|::.:..|:...:.::|.:|......||..
  Fly    46 DKAIEGAGFGIFNLMLLIVSIPAQSAAIFESSSMSYILPIAECDLRLTLEDKGVLNAVAYAGMTI 110

  Fly    72 SGLFIGFLADRYGRKFVIRLALVGALSFSVI---SALMPDLYSLSVIRIIVGTFLSAVASLQVGF 133
            |.:..|:|||..|||   ::...|.|..:|.   |||..:...|.:.:.:.|..::..|::...:
  Fly   111 SAIAWGYLADTKGRK---KILYWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTY 172

  Fly   134 LGEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRV--WRFLMMFFMIP 196
            |.|.|..|.|...:.|.......|.:..||:|..|.|.:::.:.   :.|:|  |:..:....||
  Fly   173 LTEMHGPKHRSSVLMIVGMVTSTATVSLPLLAWGIFPRDWDFEF---WGLQVHSWQIFLFVLGIP 234

  Fly   197 GWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRKKWED--------------------V 241
            ..::.:..|.:||:|.|||:..|.::||.|.|.|..:|.:|.:|                    |
  Fly   235 SLISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEV 299

  Fly   242 DITLSEEKSSTNDQEGFWKTV-------WYEYKLLFSKPHVFKFFICLFLIFGIFFTSIGLGIWF 299
            ..|: ||||.....:...:|:       ..:.|.|..||.:.....|..:.||||.....:.:|.
  Fly   300 IYTI-EEKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWL 363

  Fly   300 PVI-------------RNMDNSGSNRLCDLVNNNPTFINHEADDT-NGTDS-ESPKCNDEMTNLI 349
            |.:             ..:|.|    :|.::..:   :|..|:.. |..|: ..||.......|.
  Fly   364 PQLFASMAEYEALHAGDGLDVS----MCTILEFS---VNQTAETALNYADACSEPKVISMDMYLN 421

  Fly   350 DPVYYGFTYIGCFILASVLVHWMTRKYVIALHILISMILGISLNIMKQPTVVLIFFVLMMVLPGV 414
            :.:.....::|.|....:| ..:..|.::...:.:|...|:.|.......:.||.....:.:.|:
  Fly   422 NIIVSATGFVGYFFAGGIL-RALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLTITGI 485

  Fly   415 LIPLATSVLVDCLPVNLRGKALCMVRSLARFGGVLGSTMIGLFIRVTCDVTFNIFNLCLAICVVL 479
            .:......:|...|..||...:.:.....|||.:.|:.:..:|::..|...|.:.:..|.:..:|
  Fly   486 AVSSLLGAVVALFPTQLRTVVVAIAMMCGRFGALSGNLLFPVFVQTGCLPPFIMVSSVLILSGIL 550

  Fly   480 AVFQP 484
            ::..|
  Fly   551 SISLP 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	105/475 (22%)
		MFS	23..>208	CDD:119392	45/189 (24%)
		MFS	354..>482	CDD:304372	23/127 (18%)
CG31272	NP_650013.3	MFS	62..555	CDD:119392	111/507 (22%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	104/464 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458182
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	1	0.950	-	0	Normalized mean entropy	S5294
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.950