DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33233 and CG15221

DIOPT Version :9

Sequence 1:	NP_995978.2	Gene:	CG33233 / 2769005	FlyBaseID:	FBgn0053233	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	126/500 - (25%)
Similarity:	239/500 - (47%)	Gaps:	40/500 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DTALLTIGYGLGQVIIFMVSFFIYMYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSLLGGMVA 71
            :.|:...|.|.....:.::....:|..:.|.|....::....|:...:..::.:||::...|:|.
  Fly    35 EEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQMKCDLQPTLNQQGILASAGFLGVVL 99

  Fly    72 SGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQVGFLGE 136
            |...:|||||.:||...:|.||..:...|::||...:::.|.|.|.:.|.|:|...:......||
  Fly   100 SSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGFFISGGQACVFSLCGE 164

  Fly   137 FHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFLMMFFMIPGWLAL 201
            ||....|...|.:.|....:|:|:.|.:|:.|||..... :....:...||.|::..:....|||
  Fly   165 FHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIET-IVLGMHFSSWRVLLLANVSIPLLAL 228

  Fly   202 VGICLVPETPHFLMSVNRPDKALLALKWICRMNR----KKWEDVDITLSEEKSSTNDQEGFW--- 259
            |||..:||||.:|:...|.|::|..|:.|...|.    .::...::.|.....|.:|..||.
  Fly   229 VGISALPETPKYLLVQGRGDESLEVLRSIFANNSGRDPSEYPVKEVALESGGVSLSDVHGFLDAV 293

  Fly   260 KTVWYEYKLLFSKPHVFKFFICLFLIFGIFFTSIGLGIWFPVI------RNMDNSGSNRLCDLVN 318
            :.||::...||.:..::.......:.|.|:|.:.|:.:|||.|      ||.:|:   .||.::.
  Fly   294 RLVWHQTVPLFYRARLWHTLNICCIQFIIYFLAQGIFMWFPTILDELGTRNGENT---LLCTVLQ 355

  Fly   319 N-NPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYI--GCFI----LASVLVHWMTRKY 376
            . |   ||..::|      |:..|:.|    :|...|....|  .||:    :.:.::.:|.:|.
  Fly   356 GFN---INSSSED------EASSCSVE----VDTSTYQVMIIIAACFVVIYLIFAYIIDYMGKKN 407

  Fly   377 VIALHILISMILGISLNIMKQPTVVLIFFVLMMVLPGVLIPLATSVLVDCLPVNLRGKALCMVRS 441
            ::...::::||..::|:.::|..:|:|...::|.: |....|.:::.::..|.::....:|.:..
  Fly   408 LLMAWMVLTMICLVALHYVEQFALVVIALTVVMAI-GNCGGLVSTIAMEFYPTHINAMGMCFIMM 471

  Fly   442 LARFGGVLGSTMIGLFIRVTCDVTF-NIFNLCLAICVVLAVFQPK 485
            :.|.|.|:||.::|..:..:||..| .:..|.:.:| .|..|.|:
  Fly   472 VGRLGAVVGSNILGRLLFASCDPIFWALLALVVLLC-TLGYFLPE 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	112/448 (25%)
		MFS	23..>208	CDD:119392	51/184 (28%)
		MFS	354..>482	CDD:304372	29/134 (22%)
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	118/469 (25%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	115/454 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473169
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BJZM
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.900