DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33233 and CG3168

DIOPT Version :9

Sequence 1:	NP_995978.2	Gene:	CG33233 / 2769005	FlyBaseID:	FBgn0053233	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	509	Identity:	115/509 - (22%)
Similarity:	212/509 - (41%)	Gaps:	59/509 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DTALLTIGYGLGQVIIFMVSFFIYMYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSLLGGMVA 71
            :.|:...|||....|:..:...:......:.::..:::....|:.|.:.:.|..|.:.:..||:.
  Fly   138 ERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIFIGMMV 202

  Fly    72 SGLFIGFLADRYGRKFV-IRLALVGALSFSVISALMPDLYSLSVI-RIIVGTFLSAVASLQVGFL 134
            ...|.|.:||.:|||.| |.::.:.|  |.::::.....||..:: |.:.|..|.....:...:.
  Fly   203 GAYFWGSIADSFGRKKVLIVISFMNA--FCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYF 265

  Fly   135 GEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSY-NLRVWRFLMMFFMIPGW 198
            .||.....|...::..:.......::...:|..|:|.  .:..::.| ....||..::...:|.:
  Fly   266 AEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPR--TIGFTTPYFTYNSWRIFLLVCSLPSF 328

  Fly   199 LALVGICL--VPETPHFLMSVNRPDKALLALKWICRMNRKKWED--------VDITLSEEKSSTN 253
              |||..|  :||:|.||::..:.|:||...:.|...|.|:..|        ||..|.|...:..
  Fly   329 --LVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGNVK 391

  Fly   254 DQEGFWKTVWYEY-KLLFSKPHVFKFFICLFLI-FGIFFTSIGLGIWFPVIRNM----------D 306
            ::.....:...:: :.||..| :.:|.|....| |.......||.:|||.:.|.          .
  Fly   392 NKYSRMISGMVDHSRALFKSP-ILRFTIVSITINFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQ 455

  Fly   307 NSGSNRLCDLVNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYIGCFILASVLVHW 371
            ::|...:.|.|.|..     :....|||.|.....:..|.:||...    :.:...:||.:.:..
  Fly   456 SAGVCAVTDYVVNLA-----KEQSNNGTCSSDIPQSVFMESLISLA----SALPANLLAILGMDM 511

  Fly   372 MTRKYVIALHILISMILGISLNIMKQPTVVLIFFVLMMVLPGVLIPLATSVLVDCL-----PVNL 431
            :.||:.:   |..:|..||...:|......:...|:..:..|.:  .|.:..:|||     |..|
  Fly   512 LGRKFFL---IAGTMTAGICSALMYFVRSSVQNLVVSAIFSGAI--SAANAALDCLITEVFPTKL 571

  Fly   432 R--GKALCMVRSLARFGGVLGSTMIGLFIRVTC-DVTFNIFNLCLA---ICVVL 479
            |  |.|:.||  .||.||::|:.:|...:...| ..||.:..|.:.   :|::|
  Fly   572 RATGVAISMV--AARLGGIIGNIVIAQLLDNYCPSPTFIVSGLLIGGGLMCLLL 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	102/460 (22%)
		MFS	23..>208	CDD:119392	36/189 (19%)
		MFS	354..>482	CDD:304372	34/137 (25%)
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	105/471 (22%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	109/491 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	1	0.950	-	0	Normalized mean entropy	S5294
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.020