Protein Alignment CG33233 and Slc22a2

DIOPT Version :10

• Sequence 1: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_113772.1
• Gene: Slc22a2 / 29503
• RGDID: 61936
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 415
• Identity: 103/415 - (24%)
• Similarity: 173/415 - (41%)
• Gaps: 97/415 - (23%)

  Fly    68 GMVASGLFIGFLADRYGRKFVIRLA-LVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQV 131
            |.....:.||:||||:||||.:.:. |:.|:| ..:.|:.|:...:.|.|.:.|  |.:.|...:
  Rat   159 GFFIGAMMIGYLADRFGRKFCLLVTILINAIS-GALMAISPNYAWMLVFRFLQG--LVSKAGWLI 220

  Fly   132 GF--LGEFHAIKWRPITVAICSQ---SQGLALIYCPLVAMA-ILPNNFNVDLSSSYNLRVWRFLM 190
            |:  :.||..:.:|.: |.||.|   :.||.:    |..:| ::||              ||:|.
  Rat   221 GYILITEFVGLGYRRM-VGICYQIAFTVGLLI----LAGVAYVIPN--------------WRWLQ 266

  Fly   191 MFFMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRKKWEDVDITLSEEKSSTNDQ 255
            ....:|.:..|:....:||:|.:|:|.|:..||:..:|.|.:.|.|   .|.::|   ::.|.|:
  Rat   267 FAVTLPNFCFLLYFWCIPESPRWLISQNKIVKAMKIIKHIAKKNGK---SVPVSL---QNLTPDE 325

  Fly   256 EGFWKTVWYEYKLLFSKPHVFKFFICLFLIFGIFFTSIGLGIWFPVIRNMDNSGSNRLCD----- 315
            :. .|.:......|...|.:.|.  .|.|::..|.:|:   ::..:|.:|..:|.|...|
  Rat   326 DA-GKKLKPSILDLVRTPQIRKH--TLILMYNWFTSSV---LYQGLIMHMGLAGDNIYLDFFYSA 384

  Fly   316 LVNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYIGCFILASVLV----HWMTRKY 376
            ||.....||.....|..|.     :....::|::         .|...||||.:    .|:  |.
  Rat   385 LVEFPAAFIIILTIDRVGR-----RYPWAVSNMV---------AGAACLASVFIPDDLQWL--KI 433

  Fly   377 VIA----LHILISMILGISLNIMKQPTVVLIFFVL----MMVLPGVLIP---------------- 417
            .||    :.|.::..:...:|....||.:....||    |..:.|::.|
  Rat   434 TIACLGRMGITMAYEMVCLVNAELYPTYIRNLGVLVCSSMCDIGGIITPFLVYRLTDIWMEFPLV 498

  Fly   418 ------LATSVLVDCLPVNLRGKAL 436
                  |....||..|| ..:||||
  Rat   499 VFAVVGLVAGALVLLLP-ETKGKAL 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	2A0119	<49..>295	CDD:273328	64/233 (27%)
Slc22a2	NP_113772.1	2A0119	12..525	CDD:273328	103/415 (25%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15244	284..288		2/3 (67%)