DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG33233 and Slc22a20

DIOPT Version :9

Sequence 1:NP_995978.2 Gene:CG33233 / 2769005 FlyBaseID:FBgn0053233 Length:489 Species:Drosophila melanogaster
Sequence 2:NP_001381833.1 Gene:Slc22a20 / 293686 RGDID:1311460 Length:556 Species:Rattus norvegicus


Alignment Length:532 Identity:104/532 - (19%)
Similarity:192/532 - (36%) Gaps:184/532 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 YSVTESMTAGYLVVLTSC-----------------EFDTSPKEKTL--LANSL-LGGMVASGLFI 76
            :::.|..|:.:.|....|                 |:|...:.:||  ||.|: :.|::......
  Rat    90 WALLEPNTSSHGVATEGCKDGWVYDRSIFPSTIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALF 154

  Fly    77 GFLADRYGRK-----FVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVA--SLQVGFL 134
            |.||||.|||     ..::||:.||     ::|.:....:..:.|.::|...|.:.  ||.:   
  Rat   155 GSLADRLGRKAPLVWSYLQLAVSGA-----VTAYVGSFSAYCIFRFLMGMTFSGIILNSLSL--- 211

  Fly   135 GEFHAIKWRPI---TVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFL------- 189
                .::|.|.   |||      |:.|.:...:...||       ...:|.:|.||:|       
  Rat   212 ----VVEWMPTRGRTVA------GILLGFSFTLGQLIL-------AGVAYLIRPWRWLQFAVSAP 259

  Fly   190 -MMFFMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRKKWEDVDITLSEEKSSTN 253
             ::||:...||        ||:..:|:...:..:|:..|:.:..||.:|.|...:|:  |..|:.
  Rat   260 FLVFFLYSWWL--------PESSRWLLLHGKAQQAVQNLRKVAMMNGRKAEGERLTI--EVVSSY 314

  Fly   254 DQEGFWKTVWYEYKL-LFSKPHVFKFFICLFLIFGIFFTSIGLGIWFPVIRNMDNSGSNRLCDLV 317
            .|..|.........| ||..|.:.|...||.:            :||          ||.:    
  Rat   315 IQNEFASVRTSNSILDLFRTPGIRKVTCCLMM------------VWF----------SNSV---- 353

  Fly   318 NNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYIGCFILASVLVHWMTRKYVIALHI 382
                                              .|||        ||..|     :|:.:::::
  Rat   354 ----------------------------------AYYG--------LAMDL-----QKFGLSIYL 371

  Fly   383 LISM--ILGISLNIMKQPTVVLI--------FFVL--MMVLPGVLIP-----------------L 418
            :.::  |:.|...::...|::.:        |.||  :||:..:.:|                 |
  Rat   372 VQALFGIIDIPAMLVATTTMIYVGRRATVSSFLVLAGLMVIANMFVPEDLQTLRTVQAALGKGCL 436

  Fly   419 ATSVLV------DCLPVNLRGKALCMVRSLARFGGVLGS--TMIGLFIRVTCDVTFNIFNLCLAI 475
            |:|.:.      :..|..:|...:......||.||:...  |.:|....|...|:|...::...:
  Rat   437 ASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLAAPLITTLGEISPVLPPVSFGATSVLAGM 501

  Fly   476 CVVLAVFQPKDI 487
            .|:..:.:.:::
  Rat   502 AVICFLTETRNV 513

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33233NP_995978.2 MFS_1 22..451 CDD:284993 98/492 (20%)
MFS 23..>208 CDD:119392 48/213 (23%)
MFS 354..>482 CDD:304372 30/164 (18%)
Slc22a20NP_001381833.1 MFS_SLC22A6_OAT1_like 103..508 CDD:341004 101/512 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166346906
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

Return to query results.
Submit another query.