Protein Alignment CG33233 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 529
• Identity: 110/529 - (20%)
• Similarity: 186/529 - (35%)
• Gaps: 159/529 - (30%)

  Fly     1 MPAMDVDTALLTIGYGLGQVIIFMVS--------------FFIYMYSVTES---MTAGYLVVLTS 48
            :|.:|..|:..:|...||..::..||              |....:.:|||   .|.........
Mouse    51 VPLLDNSTSQASIPGDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAATEP 115

  Fly    49 CE----FDTSPKEKT------LLANS----------LLGGMVASGLFIGFLADRYGRKFVIRLAL 93
            ||    :|.|....|      |:.||          .|.|::......|..:||:||:.|:..:.
Mouse   116 CEDGWVYDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSY 180

  Fly    94 VGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQVGFLGEFHAIKWRPITVAICSQSQGLAL 158
            :........:|.||......:.|.::.:.::.|.......|     ::|        :.:||..|
Mouse   181 LLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLL-----MEW--------TSAQGSPL 232

  Fly   159 IYCPLVAMAILPNNFNVDLSSS--YNLRVWRFLMMFFMIPGWLALVGICLVPETPHFLMSVNRPD 221
            :    :.:..|..:|...|:.|  |.:|.||.|.:....|.:|..|....:||:..:|::|.:.|
Mouse   233 V----MTLNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLD 293

  Fly   222 KALLALKWICRMNRKKWEDVDITL-----SEEKSSTNDQEG-----FWKTVWYEYKLLFSKPHVF 276
            :.|..|:.:..:||:|.|...:|:     :.|:..:.|:.|     ...|....::.:.|
Mouse   294 QGLQELQRVAAVNRRKAEGDTLTMEVLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIIS----- 353

  Fly   277 KFFICLFLIFGIFFTSIGLGIW-----------------FPVIRNMDNSGS--------NRLCDL 316
              .:|.| .||..|..:.|.:.                 |||     .:||        .|||
Mouse   354 --MLCWF-AFGFTFYGLALDLQALGSNIFLLQALIGIVDFPV-----KTGSLLLISRLGRRLC-- 408

  Fly   317 VNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYIGCFILASVLV-HWMTRKYVIAL 380
                                       :::.|:.|        |..||:::|| |.|
Mouse   409 ---------------------------QVSFLVLP--------GLCILSNILVPHGM-------- 430

  Fly   381 HILISMILGISLNIMKQPTVVLIFFVLMMVLPGVLIP-LATSVLVDCLPVNLRGKALCMVRSLAR 444
            .:|.|.:..:.|..:...      |..:.:....|.| :.....|....|..||.|  |:..|.|
Mouse   431 GVLRSALAVLGLGCLGGA------FTCITIFSSELFPTVIRMTAVGLCQVAARGGA--MLGPLVR 487

  Fly   445 FGGVLGSTM 453
            ..||.||.|
Mouse   488 LLGVYGSWM 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	101/504 (20%)
		MFS	23..>208	CDD:119392	45/223 (20%)
		MFS	354..>482	CDD:304372	26/102 (25%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	110/529 (21%)
		MFS	147..516	CDD:119392	89/433 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843302
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840