Protein Alignment CG33233 and sv2b

DIOPT Version :10

• Sequence 1: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_002933355.1
• Gene: sv2b / 100497731
• XenbaseID: XB-GENE-6041859
• Length: 711
• Species: Xenopus tropicalis
• Alignment Length: 568
• Identity: 119/568 - (20%)
• Similarity: 210/568 - (36%)
• Gaps: 116/568 - (20%)

  Fly     3 AMDVDTALLTIGYGLGQVIIFMVSFFIYMYSVTESMTAGYLVVLTSCEFD--TSPKEKTLLANSL 65
            |...:..:...|:|..|..:|:|.....|....|....|:  ||.|.|.|  .|...|.:|...:
 Frog   120 AYQYENIIQECGHGRFQWTLFVVLGLALMADGVEVFVVGF--VLPSAEKDMCLSRSNKGMLGLIV 182

  Fly    66 LGGMVASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQ 130
            ..||:......|.|||:.|||..:.::|....:||.:|:.:.........|:|.|..:.....:.
 Frog   183 YLGMMLGAFVWGGLADKVGRKKCLIISLTINAAFSFVSSFVQGYGLFLFCRLISGFGIGGSLPIV 247

  Fly   131 VGFLGEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPN-NFNVDLSSSYNLRVWRFLMMFFM 194
            ..:..||.|.:.|...::.......:..:|...:|.:|:|: .:...:.:.|:...||..::..:
 Frog   248 FAYFSEFLAREKRGEHLSWLCMFWMIGAVYAAAMAWSIIPHYGWGFSMGTHYHFHSWRVFVVICV 312

  Fly   195 IPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMN-RKKWEDVDI-TLSEEKSSTNDQE- 256
            :|...:::.:..:||:|.||:...:.|:|.:.||.|...| |.|.|...: |:|..|:.....|
 Frog   313 LPCIASIIALKFMPESPRFLLETGKHDEAWMILKNIHDTNMRAKGEPEKVFTVSHIKTPKQPDEF 377

  Fly   257 -------GFWKTVWYEYKLLFSKP------HVF-----KFFICLFLI-FGIFFTSIGLGIWFP-V 301
                   |.|...|:...:...|.      |.|     |..|.|.:: |.:..:..||.:||| .
 Frog   378 IEIQSSTGTWFQRWFVRIMTVIKQIWENMLHCFSGQFRKNTIFLAVVWFTMSLSYYGLTVWFPDT 442

  Fly   302 IRNM-DNSGSNRLCDLVNNNPTFINHEADDTNGTDSESPKCNDEM-----------TNLIDPVYY 354
            ||.: |...::::....:.|....|......|....:....||..           .:|.|..|:
 Frog   443 IRYLQDEDYASKVKRFTDENVKNFNFNFTLENQIHEDGEYYNDRFYKMKLKYVTFKDSLFDECYF 507

  Fly   355 ------GFTYIGCFILASVLVHWMTRKYVIALHILISM-ILGISLNIMKQPTVV--------LIF 404
                  |..:..|.|..:|.  :.|..|   .|..|.. .:.::.:..|:...:        ||:
 Frog   508 EDVTSTGSIFENCTIQNTVF--YNTDLY---QHKFIDCNFINVTFSQPKEGCHIDFEEDNDFLIY 567

  Fly   405 FVLMM----VLPGVLIP------------LATSVLV--------------------DCL------ 427
            .|..:    ||||.:|.            :|.|:|:                    .||
 Frog   568 LVSFLGSLSVLPGNIISALLMDKIGRIRMIAGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSI 632

  Fly   428 --------------PVNLRGKALCMVRSLARFGGVLGSTMIGLFIRVT 461
                          |.|.|..|..::..|.:...:.|:::...|:.:|
 Frog   633 AAWNALDVVTVELYPTNKRATAFGILNGLCKLAAIFGNSIFASFVGIT 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	2A0119	<49..>295	CDD:273328	61/270 (23%)
sv2b	XP_002933355.1	synapt_SV2	1..711	CDD:130366	119/568 (21%)