DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment zormin and gpatch3

DIOPT Version :9

Sequence 1:NP_001261317.1 Gene:zormin / 2769001 FlyBaseID:FBgn0052311 Length:3664 Species:Drosophila melanogaster
Sequence 2:XP_005158511.1 Gene:gpatch3 / 791148 ZFINID:ZDB-GENE-070112-902 Length:688 Species:Danio rerio


Alignment Length:467 Identity:105/467 - (22%)
Similarity:163/467 - (34%) Gaps:112/467 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly  2178 NGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGR 2242
            :|.|..:.:...:.|.|     .:::|.|.:               .|..||      ||.....
Zfish    95 SGNQWIDSSGNWLRNTC-----LIRRVRVSE---------------QSDCDL------FPYKTKA 133

  Fly  2243 RLQAQVSKKGEKLTMEVEVTGLPE---PTVTWLKDDKPLKDAGISEHRLLAQGNSYRL---IIEK 2301
            .|:..|: :.|:.| |.::.||||   |.:      .|..:.|......|....|.||   :|.|
Zfish   134 ELRRHVA-QSEQFT-ENDLRGLPELNPPAL------MPSGNVGTPVSVFLQLIQSCRLPPRLIRK 190

  Fly  2302 A----QTTDSGK------YMVRAT-----------NAGG-EAKSIADCAILEPSPERLQEVVKTI 2344
            .    ..|.|.:      |....|           .||| |.|..|...  .|:....::...|.
Zfish   191 LGLTFPKTGSNRRYGNVPYQYHNTRVVTPAEESVFTAGGVEIKGHAQRD--TPTTSHRKQGKPTT 253

  Fly  2345 VYETGPVAPASEFKTE---VQKQIQNS-ENQQSYQNSQTEVTSANDLHGLSESKVITEHRCTTEA 2405
            :|.|.....||:.|.:   :...||:: ...|:.|::.:......|....|:.|..|.   ||..
Zfish   254 LYRTQETPTASQAKQDTPTISLTIQDTPTTTQTNQDTPSTSCKIQDTPTASQRKQDTP---TTSQ 315

  Fly  2406 TMRLEHKS-NYLDLPELTTRPK-TPTTNDTITITTNTATVSMDQPDLTQPTITNTTT-----TNT 2463
            .:.:...| ...|.|..:.|.: ||||:..|..|..|:....|.|..:|....:||:     |.|
Zfish   316 KLDMSTTSCKIQDTPTASQRKQDTPTTSCIIQDTPTTSQTVQDTPTTSQKQDMSTTSCKIQDTPT 380

  Fly  2464 TKVPPPVPPKPCTPVVATTFGQQQQQPPQTL----TSTRYEQSEHKSTTSSSSFD----YFKKID 2520
            .......||..|......|..|::..||.:.    |.|..:.....:.|:|....    |.:.:.
Zfish   381 ASQRKDTPPTSCIIQDTPTASQRKDTPPTSCIIQDTPTTSQTKRLNTPTASRKIQDTPTYTQTLY 445

  Fly  2521 EETIIQRPNPLTFKPLDTVVRQP-QAQSLAEELRSLNLIPGDAPEFC---------YSPKTERSE 2575
            |:|    |:|        .|.|| |.:...|||..    |.|..:.|         :...|.:..
Zfish   446 EDT----PSP--------PVNQPSQEEESEEELSG----PDDDDDRCEEWERHEALHEDITAQER 494

  Fly  2576 PKIPLITEKIKI 2587
            .|..|..|:|::
Zfish   495 SKERLFEEEIEL 506

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
zorminNP_001261317.1 SPEC 126..332 CDD:238103
SPEC <504..641 CDD:295325
COG1340 960..1298 CDD:224259
RILP-like <1190..1315 CDD:304877
MAP7 1233..1365 CDD:283355
I-set 1390..1479 CDD:254352
IGc2 1403..1469 CDD:197706
I-set 1491..1580 CDD:254352
IGc2 1504..1570 CDD:197706
I-set 1589..1675 CDD:254352
Ig 1605..1675 CDD:299845
I-set 1702..1786 CDD:254352
Ig 1713..1786 CDD:299845
I-set 1811..1902 CDD:254352
Ig 1828..1892 CDD:143165
I-set 1927..2015 CDD:254352
IGc2 1940..2005 CDD:197706
I-set 2142..2231 CDD:254352 9/52 (17%)
Ig 2158..2231 CDD:299845 9/52 (17%)
I-set 2238..2325 CDD:254352 27/114 (24%)
Ig 2254..2324 CDD:299845 24/97 (25%)
I-set 3566..3655 CDD:254352
Ig 3583..3650 CDD:143165
gpatch3XP_005158511.1 RRM_SF 12..>31 CDD:302621
G_patch 585..631 CDD:197727
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1181
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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