DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zormin and Ibsp

DIOPT Version :9

Sequence 1:	NP_001261317.1	Gene:	zormin / 2769001	FlyBaseID:	FBgn0052311	Length:	3664	Species:	Drosophila melanogaster
Sequence 2:	NP_036719.2	Gene:	Ibsp / 24477	RGDID:	2855	Length:	319	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	56/266 - (21%)
Similarity:	85/266 - (31%)	Gaps:	66/266 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  2612 QTVQHESTTTKEVKVEYGQPIVRPAAVLATPAQQNPRSPSPKPSAEGVAMSRLWTPTGVTGYTSD 2676
            |..:.|:.|...|...||......|..|...|.|.|:...   .|||.|...         ..||
  Rat   101 QEAEAENATLSGVTASYGVETTADAGKLELAALQLPKKAG---DAEGKAPKM---------KESD 153

  Fly  2677 VEQKSEKTVISKLATPTPTKELNAPFLVNQIAKSIPPTTAPVTHLVNVELEPGTPPEICFAPKVE 2741
            .|::.|:          ..:..|....|::..:.:..|:...|     |::.|..|.  .....|
  Rat   154 EEEEEEE----------EEENENEEAEVDENEQVVNGTSTNST-----EVDGGNGPS--GGDNGE 201

  Fly  2742 ETRRRSLVE-----TMEQKLEQNLIQGPSKVLPHSVPTLTPNTAAPVQPKPLGNTTYRPPPPVLP 2801
            |....|:.|     |.....|.......:.||.:.....||      .|:..|.|:    ||...
  Rat   202 EAEEASVTEAGAEGTTAGARELTSYGTTTAVLLNGFQQTTP------PPEAYGTTS----PPARK 256

  Fly  2802 TRLGVYESDYESDRYKYSGSESDVEPGIRKQPQLTTMETSFKSSG------YTADTEEHSSYRKS 2860
            :....|..:||....:|:                |..||..:::|      |.|..:|:|.|:..
  Rat   257 SSTVEYGEEYEQIGNEYN----------------TAYETYDENNGEPRGDTYRAYEDEYSYYKGH 305

  Fly  2861 ESSFYE 2866
            ....||
  Rat   306 GYEGYE 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zormin	NP_001261317.1	SPEC	126..332	CDD:238103
		SPEC	<504..641	CDD:295325
		COG1340	960..1298	CDD:224259
		RILP-like	<1190..1315	CDD:304877
		MAP7	1233..1365	CDD:283355
		I-set	1390..1479	CDD:254352
		IGc2	1403..1469	CDD:197706
		I-set	1491..1580	CDD:254352
		IGc2	1504..1570	CDD:197706
		I-set	1589..1675	CDD:254352
		Ig	1605..1675	CDD:299845
		I-set	1702..1786	CDD:254352
		Ig	1713..1786	CDD:299845
		I-set	1811..1902	CDD:254352
		Ig	1828..1892	CDD:143165
		I-set	1927..2015	CDD:254352
		IGc2	1940..2005	CDD:197706
		I-set	2142..2231	CDD:254352
		Ig	2158..2231	CDD:299845
		I-set	2238..2325	CDD:254352
		Ig	2254..2324	CDD:299845
		I-set	3566..3655	CDD:254352
		Ig	3583..3650	CDD:143165
Ibsp	NP_036719.2	BSP_II	17..316	CDD:283165	56/266 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	59..116		4/14 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	135..224		22/117 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	237..263		7/35 (20%)
		Cell attachment site	288..290		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900