DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33230 and RKM2

DIOPT Version :9

Sequence 1:	NP_995955.1	Gene:	CG33230 / 2768998	FlyBaseID:	FBgn0053230	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_010484.1	Gene:	RKM2 / 851779	SGDID:	S000002606	Length:	479	Species:	Saccharomyces cerevisiae

Alignment Length:	528	Identity:	120/528 - (22%)
Similarity:	201/528 - (38%)	Gaps:	160/528 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KKSDE---------------------NSGSL--HDLYVHLHSVGWQN-HT---HLSAQYYEQTGR 50
            ||||:                     :.||:  :|:.|.:.|....| ||   |:|....|....
Yeast    13 KKSDKFYIAPNISICESPETGRGIVLSHGSIRKNDIIVSVPSSKQLNFHTILYHISKFNKELNIP 77

  Fly    51 GLCSKQKTFSPEDELIRLPIGCLISIATLESD---------GPFKSLFDEELFDKDSRISFQALI 106
            |:...:|..:.||.:|             |::         |.:..|..|.|.   |..||| |:
Yeast    78 GITIDRKPINYEDNII-------------EAENKAWADPRYGLYSELSKEFLL---SLSSFQ-LV 125

  Fly   107 ACYILYHKHLQECTLGTHSSTYA---AYLDTLPRCYSTPYFCSIPELQCLP-----------ESL 157
            :.|||....|  ....||:..|:   .:.|..|         |:.||:.:|           .||
Yeast   126 SFYILVENFL--LPKWTHNEIYSDWKPFFDVWP---------SMEELRSIPAIWNCDPNSRYHSL 179

  Fly   158 LERTVAQNRQ--------IRGYFEIIKNIVHKCD------CCGKS----YGQEIWTLADFKWAYF 204
            :|...|.:|:        :|..:|.|..:|.|.:      .|.|:    ...|:::|  |...||
Yeast   180 IEYLPAASRKHMARISGLVREDWETISEVVLKWNEIYGSLSCTKNSDKFTSDELFSL--FVHVYF 242

  Fly   205 SVNTRSVHLSSRFLKKQSNYFQPLISGD--TNLALAPFLDLFNH---SD-----QVEITAGIEGP 259
            .:|:|.::...           ||...|  :|..|.|::|..||   ||     |:......||.
Yeast   243 IINSRCLYAKI-----------PLKIEDSPSNFTLVPYVDFMNHICESDLHCYPQLSPQLRSEGE 296

  Fly   260 DYV----LTLKSLPFSETKPYDQLFISYGALPNFKLLTEYGFWLRENKHDYFEVSLLDIEHMIKQ 320
            :.:    .|::..........::||::|||..|..||.||||.:..||.:|.::|...||.:...
Yeast   297 NIIGIGQFTIRCGDHLYDNINEELFLNYGAHSNDFLLNEYGFVVDGNKWNYLDISDEIIELIDDD 361

  Fly   321 NKELSTQTFHRNIFKFIREHN------LND-----QMFVHIDDGCSHNLRVVLHLI--FKQQAYF 372
            .||:.|         |:.||:      :|:     ::||.::...:.:.|.|...|  :..:.||
Yeast   362 KKEVKT---------FLLEHDYWGDYTINETDISYRIFVALNYYVTRDERRVRKFIEGYISEDYF 417

  Fly   373 ----PNILNQIAFGDAEQFQDVQPELSYLVEYKIKEYEIFGGELDKLPKLTESGAVARSYLQECI 433
                .::|.::......::.....||:..|           ..|:....|.....:.:.|::...
Yeast   418 KPKISSVLKELLVSLTAKYTKTLSELTEKV-----------SNLENNLCLQNLITIYKGYIKILT 471

  Fly   434 RYLVDFQS 441
            ::|.|.||
Yeast   472 QHLQDLQS 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33230	NP_995955.1	T6SS_VipB	<229..>314	CDD:301628	29/98 (30%)
RKM2	NP_010484.1	SET_SETD4	20..340	CDD:380954	85/360 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I2979
eggNOG	1	0.900	-	-		E1_KOG1337
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005857
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105100
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1321
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.740