Protein Alignment CG33230 and SETD6

DIOPT Version :9

• Sequence 1: NP_995955.1
• Gene: CG33230 / 2768998
• FlyBaseID: FBgn0053230
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001153777.1
• Gene: SETD6 / 79918
• HGNCID: 26116
• Length: 473
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 86/437 - (19%)
• Similarity: 148/437 - (33%)
• Gaps: 121/437 - (27%)

  Fly    49 GRGLCSKQKTFSPEDELIRLPIGCLISIATLESDGPFKSLFDEELFDKDSRISFQALIACYILYH 113
            |.|:.:::...:.| .|..:|...|:|..|....|    |.:.|.....|:..:..|:..  |.|
Human    74 GYGMVARESVQAGE-LLFVVPRAALLSQHTCSIGG----LLERERVALQSQSGWVPLLLA--LLH 131

  Fly   114 KHLQECTLGTHSSTYAAYLDTLPRC--YSTPYFCSIPELQCL------PESLLERTVAQNRQIRG 170
            :      |...:|.:..|....|..  ...|.|....|.:||      ||: :|:.:|   .||.
Human   132 E------LQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEA-VEKDLA---NIRS 186

  Fly   171 YFEIIKNIVHKCDCCGKSYGQEIWTLADFKWAY---FSVNTRSVHLSSRFLKKQSNY-FQ-PLIS 230
            .::.|                    :..|..|:   ||:..||:.|..:.:.....| || ||..
Human   187 EYQSI--------------------VLPFMEAHPDLFSLRVRSLELYHQLVALVMAYSFQEPLEE 231

  Fly   231 GD-----TNLALAPFLDLFNHSDQVEITAGIEGPDYVLTLKSLPFSETKPY---DQLFISYGALP 287
            .:     .:..:.|..|:.||  .....|.:|     .:...|....|:|.   .::|.:||.:.
Human   232 EEDEKEPNSPVMVPAADILNH--LANHNANLE-----YSANCLRMVATQPIPKGHEIFNTYGQMA 289

  Fly   288 NFKLLTEYGFW--LRENKHDYFEVSLLDIEHMIKQNKELSTQ---TFHR-------------NIF 334
            |::|:..|||.  ..:|..|..::.::.:.....|..:...:   .:.|             ..|
Human   290 NWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAF 354

  Fly   335 KFIREHNLNDQMFVHIDDGCSHNLRVVLHLIFKQQAYFPNILNQIAFGDAEQFQDVQPELSYLVE 399
            ...||..|.::           .|...|.::......|..:.:|...||     |.:.|.|..:
Human   355 VIGREEVLTEE-----------ELTTTLKVLCMPAEEFRELKDQDGGGD-----DKREEGSLTI- 402

  Fly   400 YKIKEYEIFGGELDKLPKLTESGAVARSYLQECI-----RYLVDFQS 441
                         ..:|||..|.   |..||..:     .|..|.::
Human   403 -------------TNIPKLKASW---RQLLQNSVLLTLQTYATDLKT 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33230	NP_995955.1	T6SS_VipB	<229..>314	CDD:301628	19/94 (20%)
SETD6	NP_001153777.1	SET	<247..286	CDD:279228	9/45 (20%)
		Rubis-subs-bind	338..465	CDD:286371	23/129 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1321
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940