Protein Alignment CG33230 and setd4

DIOPT Version :10

• Sequence 1: NP_995955.1
• Gene: CG33230 / 2768998
• FlyBaseID: FBgn0053230
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001039027.1
• Gene: setd4 / 564058
• ZFINID: ZDB-GENE-050808-2
• Length: 440
• Species: Danio rerio
• Alignment Length: 455
• Identity: 117/455 - (25%)
• Similarity: 199/455 - (43%)
• Gaps: 62/455 - (13%)

  Fly     1 MGRTQRRRHQRAKKSDENSGSLHDLYVHLHSV------GWQNHTHLSAQ-----YYEQTGRGLCS 54
            |.:|:.|..:||:|..........:....|..      .|.|....::|     .:..|||||.:
Zfish     1 MNKTRCRAGRRARKKRRKKHEDFSIVTLSHEAQFVLLRRWLNERGFTSQSLIPVNFHDTGRGLMA 65

  Fly    55 KQKTFSPEDELIRLPIGCLISIATLESDGPFKSLFDEELFDKDSRISFQALIACYILYHKHLQEC 119
            .| |...::.:|.||..||::.:|:     .||...:.:......||....:.|:::..:|..|
Zfish    66 TQ-TIKAKNSVISLPEECLLTTSTV-----LKSYMADYIKRWHPPISPLLALCCFLISERHHGE- 123

  Fly   120 TLGTHSSTYAAYLDTLPRCYSTPYFCSIPELQCLPESLLERTVAQNRQIRGYFEIIKNIVHKCDC 184
                 :|.:..|:|.||:.|:.|.:.....::.||.||.::...|..|.:..|...:...|....
Zfish   124 -----ASEWNPYIDILPKTYTCPLYFPDNVIELLPRSLQKKATQQKEQFQELFSSSQTFFHSLQP 183

  Fly   185 CGKSYGQEIWTLADFKWAYFSVNTRSV---HLSSRFLKKQSNYFQPLISGDTNLALAPFLDLFNH 246
            ......:|:::....:||:.|||||:|   |..|::|.::.:.:          ||||:|||.||
Zfish   184 LFNQPTEELFSQDALRWAWCSVNTRTVYMEHDQSKYLSREKDVY----------ALAPYLDLLNH 238

  Fly   247 SDQVEITAGIEGPDYVLTLKSLPFSETKPYDQLFISYGALPNFKLLTEYGFWLRENKHD--YFEV 309
            ...|::.||.........::|:  :..|.:.|.||:||...|.:||.||||....|.|.  |.::
Zfish   239 CPNVQVEAGFNKETRCYEIRSV--NGCKKFQQAFINYGPHDNHRLLLEYGFVAPCNPHSVVYVDL 301

  Fly   310 SLLDIEHMIKQNKELSTQTFHRNIFKFIREHNLNDQMFVHIDDGCSHNLRVVLHLI-FKQQAY-- 371
            ..|.: .:.:::|:|..:..:.....|:|  ||...|     ||.|..|...|.|: .|.|.|
Zfish   302 ETLKV-GLDEKDKQLKEKLLYLKDNDFLR--NLTFGM-----DGPSWRLMTALRLLSLKPQQYTR 358

  Fly   372 FPNILNQIAFGDAEQFQDVQPEL---SYLVEYKIKEYEIFGGELDKLPKLTESGAVARSYLQECI 433
            :.::|...|.....:...::..|   :.|.|..:|       .|::|.:|.| ||......|.|:
Zfish   359 WKSVLLGAAVSQDREDWCIESALKLCNNLTEDNVK-------ALERLAQLKE-GANQSGLEQLCV 415

  Fly   434  433
            Zfish   416  415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33230	NP_995955.1	SET_SETD4	36..299	CDD:380954	75/270 (28%)
setd4	NP_001039027.1	SET_SETD4	48..288	CDD:380954	73/263 (28%)
		Rubis-subs-bind	309..427	CDD:462737	30/122 (25%)