DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33230 and setd3

DIOPT Version :9

Sequence 1:	NP_995955.1	Gene:	CG33230 / 2768998	FlyBaseID:	FBgn0053230	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	XP_012823880.1	Gene:	setd3 / 549331	XenbaseID:	XB-GENE-1016707	Length:	582	Species:	Xenopus tropicalis

Alignment Length:	329	Identity:	76/329 - (23%)
Similarity:	137/329 - (41%)	Gaps:	61/329 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GRTQRRRHQRAKKSDENSGSLHDLYVHLHSVGWQNHTHLSAQYYE-----QTGRGLCSKQKTFSP 61
            |..::.|.::...|....|...|.:..|  :.|......|...:|     :.|.|| ...:....
Frog    55 GLVEKIRKKQRGLSVVFDGKREDYFPEL--MEWCKENGASTDGFELVEFPEEGFGL-KATREIKA 116

  Fly    62 EDELIRLPIGCLISIATLESD--GPFKSLFDEELFDKDSRISFQAL----IACYILYHKHLQECT 120
            |:..:.:|...|:::.:.:..  ||        |:.:| || .||:    :|.::|       |.
Frog   117 EELFLWVPRKLLMTVESAKGSVLGP--------LYSQD-RI-LQAMGNITLAFHLL-------CE 164

  Fly   121 LGTHSSTYAAYLDTLPRCYSTPYFCSIPELQCL--PESLLE-----RTVAQNRQIRGYFEIIKNI 178
            ....:|.:..|:.|||..|.||.:.:..|:|.|  .:::|:     :..|  ||...::::|:..
Frog   165 RADPNSFWLPYIKTLPNEYDTPLYFNEDEVQYLQSTQAILDVFSQYKNTA--RQYAYFYKVIQTH 227

  Fly   179 VHKCDCCGKSYGQEIWTLADFKWAYFSVNTRSVHLSSRFLKKQSNYFQPLISGD-TNLALAPFLD 242
            .:    ..|...::.:|..|::||..||.||...:             |...|. ..|||.|..|
Frog   228 PN----ANKLPLKDSFTFDDYRWAVSSVMTRQNQI-------------PTEDGSRVTLALIPLWD 275

  Fly   243 LFNHSDQVEITAGIEGPDYVLTLKSLPFSETKPYDQLFISYGALPNFKLLTEYGFWLRENKHDYF 307
            :.||::.: ||.|....|.  ..:.:...:.|..:|::|.||...|.:.:...||:...|.||..
Frog   276 MCNHTNGL-ITTGYNLEDD--RCECVALQDFKSGEQIYIFYGTRSNAEFVIHNGFFFENNLHDRV 337

  Fly   308 EVSL 311
            ::.|
Frog   338 KIKL 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33230	NP_995955.1	T6SS_VipB	<229..>314	CDD:301628	24/84 (29%)
setd3	XP_012823880.1	SET_SETD3	80..329	CDD:380953	67/290 (23%)
setd3	XP_012823880.1	Rubis-subs-bind	350..475	CDD:370401
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1321
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940