DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33230 and setd3

DIOPT Version :9

Sequence 1:	NP_995955.1	Gene:	CG33230 / 2768998	FlyBaseID:	FBgn0053230	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_956348.1	Gene:	setd3 / 337193	ZFINID:	ZDB-GENE-030131-9137	Length:	596	Species:	Danio rerio

Alignment Length:	320	Identity:	73/320 - (22%)
Similarity:	130/320 - (40%)	Gaps:	49/320 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QRRRHQRAKKSDENSGSLHDLYVHLHSVGWQNHTHLSAQYYE-----QTGRGLCSKQKTFSPEDE 64
            ::.|.::...|....|...|.:..|  :.|......|...:|     ..|.|| ...|....|:.
Zfish    58 EKIRKKQKGMSVSFEGIREDFFSEL--MAWAAECRASCDGFEISNFADEGYGL-KATKDIKAEEL 119

  Fly    65 LIRLPIGCLISIATLESD--GPFKSLFDEELFDKDSRISFQAL----IACYILYHKHLQECTLGT 123
            .:.:|...|:::.:.::.  ||        |:.:| || .||:    :|.::|       |....
Zfish   120 FLWIPRKMLMTVESAKNSVLGP--------LYSQD-RI-LQAMGNVTLALHLL-------CERAN 167

  Fly   124 HSSTYAAYLDTLPRCYSTPYFCSIPELQ-CLPESLLERTVAQNRQIRGYFEIIKNIVHKCDCCGK 187
            .||.:..|:.|||..|.||.:....|:: .|....::..::|.:.....:.....::|......|
Zfish   168 PSSPWLPYIKTLPSEYDTPLYFEEEEVRHLLATQAIQDVLSQYKNTARQYAYFYKVIHTHPNASK 232

  Fly   188 SYGQEIWTLADFKWAYFSVNTRSVHLSSRFLKKQSNYFQPLISGD-TNLALAPFLDLFNHSDQVE 251
            ...::.:|..|::||..||.||...:             |...|. ..|||.|..|:.||::.:
Zfish   233 LPLKDAFTFDDYRWAVSSVMTRQNQI-------------PTADGSRVTLALIPLWDMCNHTNGL- 283

  Fly   252 ITAGIEGPDYVLTLKSLPFSETKPYDQLFISYGALPNFKLLTEYGFWLRENKHDYFEVSL 311
            ||.|....|.  ..:.:...:.|..:|::|.||...|.:.:...||:..:|.||..::.|
Zfish   284 ITTGYNLEDD--RCECVALKDYKEGEQIYIFYGTRSNAEFVIHNGFFFEDNAHDRVKIKL 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33230	NP_995955.1	T6SS_VipB	<229..>314	CDD:301628	24/84 (29%)
setd3	NP_956348.1	S-adenosyl-L-methionine binding. /evidence=ECO:0000250\|UniProtKB:Q86TU7	104..106		0/1 (0%)
		SET	<275..314	CDD:279228	10/41 (24%)
		S-adenosyl-L-methionine binding. /evidence=ECO:0000250\|UniProtKB:Q86TU7	275..279		1/3 (33%)
		S-adenosyl-L-methionine binding. /evidence=ECO:0000250\|UniProtKB:Q86TU7	325..327		0/1 (0%)
		Rubis-subs-bind	353..475	CDD:286371
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	556..596
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1321
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940