DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33230 and setd6

DIOPT Version :9

Sequence 1:	NP_995955.1	Gene:	CG33230 / 2768998	FlyBaseID:	FBgn0053230	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_955894.1	Gene:	setd6 / 322348	ZFINID:	ZDB-GENE-030131-1067	Length:	460	Species:	Danio rerio

Alignment Length:	331	Identity:	70/331 - (21%)
Similarity:	121/331 - (36%)	Gaps:	101/331 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 QRAKKSDENS--GSLHDLYVHLHSVGWQNHTHLSAQYYEQTGRGLCSKQKTFSPED-----ELIR 67
            :|.|..||.|  ..|::..:...||    ...||.:.| .:..|..::....:.||     .|..
Zfish     6 KRPKTGDEKSVLEPLNNFLLWCESV----QLTLSDKVY-LSKEGTAAEYGMLAKEDIEEGHVLFT 65

  Fly    68 LPIGCLISIATLESDGPFKSLFDEELFDKDSRISFQALIACYILYHKHLQECTLGTHSSTYAAYL 132
            :|...|:...|.:    .|.:.:|.....:|...:..|:.. ::|     |.|..|  |.:..||
Zfish    66 IPREALLHQGTTK----VKKVLEEGKKCLESASGWVPLLLS-LMY-----EYTSST--SHWKPYL 118

  Fly   133 DTLP--RCYSTPYFCSIPELQC--------LPESLLERTVAQNRQIRG-YFEIIKNIVHKCDCCG 186
            ...|  |....|.|.|  |.:|        :|||:    :...|:::. |..::...:
Zfish   119 SLWPDFRTLDQPMFWS--EEECDKLLKGTGIPESV----ITDLRKLQDEYNSVVLPFM------- 170

  Fly   187 KSYGQEIW-----------TLADFKWAYFSVNTRSVHLSSRFLKKQSNYFQPLISGD-------- 232
            ||: .::|           :|..|..||                   ::.:|:...|
Zfish   171 KSH-PDLWDPEKHNLELYKSLVAFVMAY-------------------SFQEPVEDDDEDEEDDEK 215

  Fly   233 -TNL-ALAPFLDLFN----HSDQVEITAGIEGPDYVLTLKSLPFSETKPYDQLFISYGALPNFKL 291
             .|| .:.|..|:.|    |:..:|.|     |:   .||.:........:::|.:||.:.|::|
Zfish   216 KPNLPMMVPMADMLNHISKHNANLEYT-----PE---CLKMVSIRRIGKGEEVFNTYGQMANWQL 272

  Fly   292 LTEYGF 297
            |..|||
Zfish   273 LHMYGF 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33230	NP_995955.1	T6SS_VipB	<229..>314	CDD:301628	21/83 (25%)
setd6	NP_955894.1	SET	<226..265	CDD:279228	9/46 (20%)
setd6	NP_955894.1	Rubis-subs-bind	317..449	CDD:286371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1321
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940