DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33230 and setd6

DIOPT Version :9

Sequence 1:	NP_995955.1	Gene:	CG33230 / 2768998	FlyBaseID:	FBgn0053230	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_001096520.1	Gene:	setd6 / 100125156	XenbaseID:	XB-GENE-998235	Length:	454	Species:	Xenopus tropicalis

Alignment Length:	307	Identity:	70/307 - (22%)
Similarity:	107/307 - (34%)	Gaps:	96/307 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 SKQKTFSPEDELIR-LPIGCLIS--------------IATLESDGPFKSLFDEELFDKD------ 97
            :|::....||.|.. ||:.|.::              |:|..:...:..|..|:|.|.:
Frog     5 AKKQKLQSEDHLQNDLPVSCFLAWCKKVGLELNPKVYISTEGTVSQYGMLAREDLSDGELLFSIP 69

  Fly    98 -SRISFQALIACYILYHKH---LQECT-----------LGTHSSTYAAYLDTLPRCYSTPYFCSI 147
             |.|..|.......|..|.   ||.|:           ..|.||::.|           |||...
Frog    70 RSAILSQNTTRIRDLIEKEQDSLQSCSGWVPLLISLLYEATDSSSHWA-----------PYFGLW 123

  Fly   148 PELQ--CLPESLLERTVAQNRQIRGYFEII----KNIVHKCDC-------------CGKSYGQEI 193
            |||.  .:|....|....:..|..|..|.:    |||..:.:.             |...:..::
Frog   124 PELDPPDMPMFWSEEEQTKLLQGTGILEAVHKDLKNIEKEYNSIVLPFIRRNPEKFCPMKHTLDL 188

  Fly   194 W-TLADFKWAYFSVNTRSVHLSSRFLKKQSNYFQPLISGD-TNLALAPFLDLFNHSDQ----VEI 252
            : .|..|..||            .|.:.|....:..|..| ....:.|..||.||..|    :|.
Frog   189 YKRLVAFVMAY------------SFQEPQEEDEEEDIEKDILPPMMVPVADLLNHVAQHNAHLEF 241

  Fly   253 TAGIEGPD--YVLTLKSLPFSETKPYDQLFISYGALPNFKLLTEYGF 297
            |     |:  .::|.||:...:     :||.:||.:.|::||..|||
Frog   242 T-----PECLRMITTKSVCAGQ-----ELFNTYGQMANWQLLHMYGF 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33230	NP_995955.1	T6SS_VipB	<229..>314	CDD:301628	24/76 (32%)
setd6	NP_001096520.1	SET	<225..265	CDD:307139	13/49 (27%)
setd6	NP_001096520.1	Rubis-subs-bind	314..445	CDD:312693
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1321
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940