DRSC/TRiP Functional Genomics Resources

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Protein Alignment aln and Dipk1b

DIOPT Version :10

Sequence 1:NP_995949.1 Gene:aln / 2768997 FlyBaseID:FBgn0035179 Length:407 Species:Drosophila melanogaster
Sequence 2:NP_062807.2 Gene:Dipk1b / 56279 MGIID:1927576 Length:431 Species:Mus musculus


Alignment Length:442 Identity:98/442 - (22%)
Similarity:158/442 - (35%) Gaps:136/442 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 VLIAVLLAVGIF-----------SYAFLNLKFCFKLMSHRSLNLMCQKFEKHEYSGSLCEELCGS 70
            |...:|:.:|||           ||:    :.|   ..|....::|.::.|...|||:|::||..
Mouse    29 VKYVLLVWLGIFVGSWMVYVHYSSYS----ELC---RGHVCQVVICDQYRKGIISGSVCQDLCEL 86

  Fly    71 QSSFDNFQCPLNDMKTILFTAEKNGDLYAVKLARHNDDEL-------------SWTN-------- 114
            |..         :.:|.|.:| ....:|:   ....|.|:             :|.:        
Mouse    87 QKV---------EWRTCLSSA-PGQQVYS---GLWQDKEVTIKCGIEEALNSKAWPDAAPRRELV 138

  Fly   115 -----NKGESIYPKLEEFHEIVKLHIILAY-NVTLDD-NMIRALVNQEI--ADDNSQQMVSF--- 167
                 .:|.||    :||.|:.     |:: ...|.| ..:.|||:|.:  ||.|....||.   
Mouse   139 LFDKPTRGTSI----KEFREMT-----LSFLKANLGDLPSLPALVDQILLMADFNKDSRVSLAEA 194

  Fly   168 ---WRLFKDNNYMMGKLFDEESIFPAVLGSCGPYYATEGL------------EIVQSNPSIM--- 214
               |.|.:.|.:::.....|:.....:||.||..|.|||:            .:....||::   
Mouse   195 KSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGIPHGSWHGAVLLPALRPLLPSVLHRA 259

  Fly   215 --QYLASNRVQRLKHALNIMEYIFRLDEMKPEPLKMCKMQVNRFGTASERRLKYQSAEHVYVESQ 277
              |:.......|.|.|:.::|::..|.........||:..:...|..:....|....:.|..|:.
Mouse   260 LQQWFGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEAT 324

  Fly   278 LDKRLSRGVKCHAHQDCHF-HSCRGLCDEEKQSCTHIQQNNNFQIFCEHILLGGGTFQPGLLSGV 341
            : :|..:|..|....||.: ..||..||...:.|.                  |...||      
Mouse   325 V-RRFLQGRHCEQSSDCIYGRDCRAPCDRLMRQCK------------------GDLIQP------ 364

  Fly   342 RLSKALQKLVKMCVQPPKEHQVPGRQWAPNTQLALRLYNEL-KQLHQAATAS 392
                   .|.|:| :..:::.:||   ||     ..||.|| |||....|.|
Mouse   365 -------NLAKVC-ELLRDYLLPG---AP-----AGLYEELGKQLRTCTTLS 400

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alnNP_995949.1 PIP49_N 10..153 CDD:464353 36/174 (21%)
PIP49_C 167..357 CDD:463512 42/213 (20%)
Dipk1bNP_062807.2 May mediate ER retention 5..6
PIP49_N 23..179 CDD:464353 38/178 (21%)
PIP49_C 197..399 CDD:463512 53/242 (22%)
Blue background indicates that the domain is not in the aligned region.

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