DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12038 and Dipk1c

DIOPT Version :9

Sequence 1:	NP_995949.1	Gene:	CG12038 / 2768997	FlyBaseID:	FBgn0035179	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_574179.1	Gene:	Dipk1c / 498891	RGDID:	1559694	Length:	409	Species:	Rattus norvegicus

Alignment Length:	434	Identity:	97/434 - (22%)
Similarity:	160/434 - (36%)	Gaps:	90/434 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RKIRFGMQRT-------------VLIAVLLAVGIFSYAFLNLKFCFKLMSHRSLNLMCQKFEKHE 58
            |..|:|..|.             ||.|.||   :.::..:..:.|....|.|.|..:|:.:....
  Rat    10 RVARYGRWRRGALLAFAAWTAGWVLAAALL---LRAHPSVLSERCTDEKSRRILAALCRDYRGGW 71

  Fly    59 YSGSLCEELCGSQSSFDNFQCPLNDMKTILFTAEKNGDLYAVKLARHNDDELSWTNNKGESIYPK 123
            .:|:|||:||.:...... :|...:....:..|:..|....:|..|           :..|.:|.
  Rat    72 LTGALCEDLCVAGELLYQ-RCLYYERGKKVLQAQWRGQTVVLKSKR-----------EAFSSFPP 124

  Fly   124 LEEFHE-------IVKLHIIL--------AYNVTLDDNMIRALVNQEIADDNSQQMVSFWRLFKD 173
            |....|       |.:..::|        ...:.|.:|.|..|..........|::.|.|.|.:.
  Rat   125 LNLLEEEAGPGAPIPEAELLLMVAGEVKNTLGLELPNNSIAPLWPARQGPGWRQELASAWSLLQQ 189

  Fly   174 NNYMMGKLFDEES--IFPAVLGSCGPYYATEGLEIVQSNPSIMQYLA--------------SNRV 222
            ..|:...|..:.|  |.| ||||||.:||.|             |||              :.:.
  Rat   190 EEYVYFSLLPDLSRHILP-VLGSCGHFYAVE-------------YLAAGSPHHKALFPLDDAGQA 240

  Fly   223 QRLKH-ALNIMEYIFRLDEMKPEPLKMCKMQVNRFGTASERRLKYQSAEHVYVESQLDKRLSRGV 286
            |.:.| ||:.::.:...|......|.:|.::...|....:..:.....:..:.|.::.:.|.:
  Rat   241 QAISHIALSFLDMVSHFDSDFSHRLHLCDVKPENFAIKRDFTVVAIDVDMAFFEPKMREILEQ-- 303

  Fly   287 KCHAHQDCHFHSCRGLCDEEKQSCTHIQQNNNFQIFCEHILLGGGTFQPGLLSGVR---LSKALQ 348
            .|...:||:|..|...||.....|...:.|:|.|:.|:.|      ||....|..|   :|..||
  Rat   304 NCTGDEDCNFFDCFSKCDLRVNKCGARRVNSNLQVICDKI------FQHWFSSSHRSPAISPQLQ 362

  Fly   349 KLVKMCVQPPKEHQVP-GRQWAPNT----QLALRLYNELKQLHQ 387
            ..::..||....|..| |..|..::    :|...|...||:|.:
  Rat   363 LQLQQAVQECAHHGDPSGNSWTASSSVFWKLRWLLQATLKELQE 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12038	NP_995949.1	PIP49_N	10..153	CDD:291537	34/170 (20%)
CG12038	NP_995949.1	PIP49_C	167..357	CDD:289064	50/209 (24%)
Dipk1c	XP_574179.1	PIP49_N	13..167	CDD:291537	33/168 (20%)
Dipk1c	XP_574179.1	PIP49_C	183..373	CDD:289064	51/211 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354225
Domainoid	1	1.000	58	1.000	Domainoid score	I10549
eggNOG	1	0.900	-	-		E1_28K8P
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	76	1.000	Inparanoid score	I5165
OMA	1	1.010	-	-		QHG49292
OrthoDB	1	1.010	-	-		D1035909at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto98144
orthoMCL	1	0.900	-	-		OOG6_109430
Panther	1	1.100	-	-	LDO	PTHR21093
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.770