Protein Alignment aln and DIPK1A

DIOPT Version :10

• Sequence 1: NP_995949.1
• Gene: aln / 2768997
• FlyBaseID: FBgn0035179
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001006606.2
• Gene: DIPK1A / 388650
• HGNCID: 32213
• Length: 428
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 79/402 - (19%)
• Similarity: 144/402 - (35%)
• Gaps: 111/402 - (27%)

  Fly    49 LMCQKFEKHEYSGSLCEELCGSQSSFDNFQCPLNDMKTILFTAEKNGDLY-------------AV 100
            ::|.|::.....|..|..||.:::.:.. :|         .:.:.|..:|             .:
Human    62 IICDKYKTGVIDGPACNSLCVTETLYFG-KC---------LSTKPNNQMYLGIWDNLPGVVKCQM 116

  Fly   101 KLARHNDDELSWTNNKGESIYPK------LEEFHEIV------KLHIILAYNVTLDDNMIRALVN 153
            :.|.|.|........|...::.|      :::|.|:|      ||.         |...:..|||
Human   117 EQALHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLG---------DQGNLSELVN 172

  Fly   154 --QEIADDNSQQMVSF------WRLFKDNNYMMGKLFDEESIFPAVLGSCGPYYATEGLEIVQ-- 208
              ..:||.:....||.      |.|.:.|.:::..:..::...|.::|.||..|..|.:|...
Human   173 LILTVADGDKDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLY 237

  Fly   209 --SNP-------------SIMQYLASNRVQRLKHALNIMEYIFRLDEMKPEP---LKMCKMQVNR 255
              |.|             |:.|....:..::.|.|:.::|::   :::...|   ..||......
Human   238 GISLPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFV---EDVFHGPYGNFLMCDTSAKN 299

  Fly   256 FGTASERRLKYQSAEHVYVESQLDKRLSRGVKCHAHQDCHFHS-CRGLCDEEKQSCTH--IQQN- 316
            .|...:..||......:..|:.| |.|.:...|.:..||.:.: ||..||:....||.  ||.|
Human   300 LGYNDKYDLKMVDMRKIVPETNL-KELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNL 363

  Fly   317 -NNFQIFCEHILLGGGTFQPGLLSGVRLSKALQKLVKMCV-------QPPKEHQVPGRQWAPNTQ 373
             ...|:..:::|.|..:         .:.:.|:|.:..|:       |...||.:
Human   364 AKACQLLKDYLLRGAPS---------EIREELEKQLYSCIALKVTANQMEMEHSL---------- 409

  Fly   374 LALRLYNELKQL 385
                :.|.||.|
Human   410 ----ILNNLKTL 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aln	NP_995949.1	PIP49_N	10..153	CDD:464353	21/128 (16%)
		PIP49_C	167..357	CDD:463512	45/227 (20%)
DIPK1A	NP_001006606.2	PIP49_N	19..176	CDD:464353	23/132 (17%)
		PIP49_C	194..396	CDD:463512	45/214 (21%)