DRSC/TRiP Functional Genomics Resources

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Protein Alignment aln and dipk1b

DIOPT Version :10

Sequence 1:NP_995949.1 Gene:aln / 2768997 FlyBaseID:FBgn0035179 Length:407 Species:Drosophila melanogaster
Sequence 2:NP_001090694.1 Gene:dipk1b / 100036673 XenbaseID:XB-GENE-960964 Length:431 Species:Xenopus tropicalis


Alignment Length:373 Identity:84/373 - (22%)
Similarity:138/373 - (36%) Gaps:106/373 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 LMCQKFEKHEYSGSLCEELCGSQSSFDNFQCPLNDMKTILF----TAEKNGDLYAVKLARHNDDE 109
            ::|.:::|...|||.|::||              |.:|::|    ::.....:|:   .|..|.|
 Frog    65 IICDQYKKGIISGSACKDLC--------------DERTLVFQQCLSSSPTQQVYS---GRWRDRE 112

  Fly   110 ----------LSWTNN----------------KGESIYPKLEEFHEIVK--LHIILAYNVTLDDN 146
                      |...:|                :|.|    ::||.|::.  |...|...|:|   
 Frog   113 VIIKCGVEETLKADSNPDSPPRRELVLFDKPTRGTS----MDEFKEMLGNFLKANLGEQVSL--- 170

  Fly   147 MIRALVNQ--EIADDNSQQMV------SFWRLFKDNNYMMGKLFDEESIFPAVLGSCGPYYATE- 202
              .|||:|  .:||.|:...|      |.|.|...|..::.....|:.....:||.||..|.|| 
 Frog   171 --TALVSQILTMADVNNDGKVSLAEAKSIWALLHLNEILLMLSLREKEHTSQLLGHCGDLYVTEK 233

  Fly   203 -------GLEIVQSNPSIMQYLASNRVQRLKH-------------ALNIMEYIFRLDEMKPEPLK 247
                   |.:|    |..:|.|..:.|.||.|             |:.::|::..:.........
 Frog   234 IPHDSLYGSQI----PGFLQTLLPSPVHRLVHQWCAPAWPRRAKIAIGLLEFVEEIFHGTYGSFF 294

  Fly   248 MCKMQVNRFGTASERRLKYQSAEHVYVESQLDKRLSRGVKCHAHQDCHFHS-CRGLCDEEKQSCT 311
            :|.......|...:...|......|..|..: :...:|..|..:.||.|.| |...||:..:.|.
 Frog   295 ICDSSFKNIGYNEKYDFKVVDLRKVATEMTI-RGFLKGRHCEQNSDCTFGSDCTAACDKLMKQCR 358

  Fly   312 H--IQQN--NNFQIFCEHILLGGGTFQPGLLSGVRLSKALQKLVKMCV 355
            :  ||.|  ...|:..:::|.|         |...|.:.|||.::.|:
 Frog   359 NDVIQPNLAKACQLLQDYLLYG---------SPSDLREELQKQLRTCM 397

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alnNP_995949.1 PIP49_N 10..153 CDD:464353 28/135 (21%)
PIP49_C 167..357 CDD:463512 49/215 (23%)
dipk1bNP_001090694.1 May mediate ER retention. /evidence=ECO:0000250 5..6
PIP49_N 22..179 CDD:464353 30/139 (22%)
PIP49_C 197..399 CDD:463512 49/215 (23%)
Blue background indicates that the domain is not in the aligned region.

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