Protein Alignment Muc68E and FLO1

DIOPT Version :9

• Sequence 1: NP_996064.1
• Gene: Muc68E / 2768990
• FlyBaseID: FBgn0053265
• Length: 1799
• Species: Drosophila melanogaster
• Sequence 2: NP_009424.1
• Gene: FLO1 / 851289
• SGDID: S000000084
• Length: 1537
• Species: Saccharomyces cerevisiae
• Alignment Length: 1596
• Identity: 422/1596 - (26%)
• Similarity: 590/1596 - (36%)
• Gaps: 386/1596 - (24%)

  Fly   102 APYYYQIKITSPTKIK--SLPVEVENDRKDSSGIDTTVEDLTPIPEETTTVAQETTYDPEGSTTR 164
            |.|||.:|:.....:.  :||:.|                         |:       |:|:|..
Yeast   212 AGYYYPMKVVYSNAVSWGTLPISV-------------------------TL-------PDGTTVS 244

  Fly   165 EDDTTVAIETTTEKPEDDTTVEDSTPIPEESTTVAQETTYDPEGSTTREDDTTVAIETTTEKPED 229
            :|     .|......:||.:..:.| :|:.|......||      ||.|..|.....|:||.
Yeast   245 DD-----FEGYVYSFDDDLSQSNCT-VPDPSNYAVSTTT------TTTEPWTGTFTSTSTEM--- 294

  Fly   230 DTTVEDSTPIPEESTTVAQETTYDPEGSTTRDDETTVAIETTTEKPEDDTTVEDSTPIPEESTTV 294
             |||..:..:|.:.|.:...|            .||.:...||.:|.:.|....||    |.|||
Yeast   295 -TTVTGTNGVPTDETVIVIRT------------PTTASTIITTTEPWNSTFTSTST----ELTTV 342

  Fly   295 AQETTYDPEGST-TREDDTTVAIETTTEKPEDDTTVEDSTPIPEESTTVAQETTYDPEGSTTRED 358
            .        |:. .|.|:|.:.|.|                 |..:||..  ||.:|..||
Yeast   343 T--------GTNGVRTDETIIVIRT-----------------PTTATTAI--TTTEPWNST---- 376

  Fly   359 DTTVAIETTTEKPEDDTTVEDSTPIPEESTTVAQETTYDPEGSTTREDDTTVAIETTTEKPEDDT 423
                ...|:||.    |||..:..:|.:.|.:...|            .||.....||.:|.:||
Yeast   377 ----FTSTSTEL----TTVTGTNGLPTDETIIVIRT------------PTTATTAMTTTQPWNDT 421

  Fly   424 TVEDSTPIPEESTTVAQETTYDPEGSTTREDDTTVAIET--------TTEKPEDDTTVEDSTPIP 480
            ....||    |.|||.     ...|..|  |:|.:.|.|        ||.:|.:||....||
Yeast   422 FTSTST----ELTTVT-----GTNGLPT--DETIIVIRTPTTATTAMTTTQPWNDTFTSTST--- 472

  Fly   481 EESTTVAQETTYDPEGSTTREDDTTVAIET--------TTEKPEDDTTAEDSTPIPEESTTVAQD 537
             |.|||.     ...|..|  |:|.:.|.|        ||.:|.:||....||    |.|||.
Yeast   473 -ELTTVT-----GTNGLPT--DETIIVIRTPTTATTAMTTTQPWNDTFTSTST----EITTVT-- 523

  Fly   538 TTNDPEGSTTREDDTTVAIET--------TTEKPEDDTTAEDSTPIPEESTTVAQETTYDPEGST 594
            .||   |..|  |:|.:.|.|        ||.:|.:||....||    |.|||.     ...|..
Yeast   524 GTN---GLPT--DETIIVIRTPTTATTAMTTPQPWNDTFTSTST----EMTTVT-----GTNGLP 574

  Fly   595 TREDDTTVAIETTTEKREDDTTVE--DSTPIPEESTTVAQDTTNDPEGSTTREDDTTVAIET--- 654
            |  |:|.:.|.|.|......||.|  :||   ..||:....|.....|..|  |:|.:.|.|
Yeast   575 T--DETIIVIRTPTTATTAITTTEPWNST---FTSTSTEMTTVTGTNGLPT--DETIIVIRTPTT 632

  Fly   655 -----TTEKPEDDTTAEDSTPIPEESTTVAQETTYDPEGSTTREDDTTVAIET--------TTEK 706
                 ||.:|.:||....||    |.|||.     ...|..|  |:|.:.|.|        ||.:
Yeast   633 ATTAITTTQPWNDTFTSTST----EMTTVT-----GTNGLPT--DETIIVIRTPTTATTAMTTTQ 686

  Fly   707 PEDDTTVEDSTPIPEESTTVAQETTYDPEGSTTREDDTTVAIET--------TTEKPEDDTTAED 763
            |.:||....||    |.|||...|     |..|  |:|.:.|.|        ||.:|.:||....
Yeast   687 PWNDTFTSTST----EITTVTGTT-----GLPT--DETIIVIRTPTTATTAMTTTQPWNDTFTST 740

  Fly   764 STPIPEESTTVAQDTTNDPEGSTTREDDTTVAIETTTEKREDDTTVEDSTPIPEETTTVGQETTY 828
            ||    |.|||.  .||   |..|  |:|.:.|.|.|.:....||.|..|.....|:|
Yeast   741 ST----EMTTVT--GTN---GVPT--DETVIVIRTPTSEGLISTTTEPWTGTFTSTST------- 787

  Fly   829 DPEGSTTREEDTTVAIETTTEKPEDDTTAEDSTPIPEESTTVAQETTYDPEGSTTREDDTTVAME 893
                     |.|||.  .|..:|.|:|.....||..|...|            ||.|..|.....
Yeast   788 ---------EMTTVT--GTNGQPTDETVIVIRTPTSEGLVT------------TTTEPWTGTFTS 829

  Fly   894 TTTEKREDDTTVEDSTPIPEESTTVAQDTTNDPEG--STTREEDTTVAIETTTE---------KP 947
            |:||.    ||:..:..:|.:.|.:...|... ||  |||.|..|.....|:||         :|
Yeast   830 TSTEM----TTITGTNGVPTDETVIVIRTPTS-EGLISTTTEPWTGTFTSTSTEMTTITGTNGQP 889

  Fly   948 EDDTTVEDSTPIPEETTTVGQETTYDP-EGSTTREDDTTVAIDTTTEKPEDDTTVEDSTPIPEES 1011
            .|:|.:...||..|...:    ||.:| .|:.|........:..|...|.|:|.:...||..|..
Yeast   890 TDETVIVIRTPTSEGLIS----TTTEPWTGTFTSTSTEMTHVTGTNGVPTDETVIVIRTPTSEGL 950

  Fly  1012 TTVAQDTTNDP-EGSTTREDDTTVAIDTTTEKPEDDTTVEDSTPIPEESTTIAQETTYDP-EGST 1074
            .:    ||.:| .|:.|........|..|..:|.|:|.:...||..|...:    ||.:| .|:.
Yeast   951 IS----TTTEPWTGTFTSTSTEVTTITGTNGQPTDETVIVIRTPTSEGLIS----TTTEPWTGTF 1007

  Fly  1075 TREDDTTVAIETTTEKPEDDTTVEDSTPIPEESTTVAQDTTNDPEGSTTREDDTTVAIDT-TTEK 1138
            |........:..|..:|.|:|.:...||..|...|    ||.:|...|.....|.::..| |...
Yeast  1008 TSTSTEMTTVTGTNGQPTDETVIVIRTPTSEGLVT----TTTEPWTGTFTSTSTEMSTVTGTNGL 1068

  Fly  1139 PEDDTTVEDSTPIPEESTTVAQDTTNDPEGSTTREEDTTVAIETTTEKPEDDTTVEDSTPIPEET 1203
            |.|:|.:...||    :|.::...::...|..|....::..| .|...|.:.|:|..|:.|....
Yeast  1069 PTDETVIVVKTP----TTAISSSLSSSSSGQITSSITSSRPI-ITPFYPSNGTSVISSSVISSSV 1128

  Fly  1204 TTVGQETTYDPEGSTTREDDTTVAIDTTTEKPEDDTTVEDSTPI-PEESTTVAQDTTNDPEGSTT 1267
            |:  ...|..|..|:     :.::..|||           ||.| .|.|.:....|::...||:.
Yeast  1129 TS--SLFTSSPVISS-----SVISSSTTT-----------STSIFSESSKSSVIPTSSSTSGSSE 1175

  Fly  1268 REDDTTVAIDT----TTEKPEDDTTVEDSTPIPEESTTVAQDTTNDPEGSTTREDDTTVAIDTTT 1328
            .|..:..::.:    ::|..:..|....|.|:...:||..:..::.|..:||:..:.|..:..|:
Yeast  1176 SETSSAGSVSSSSFISSESSKSPTYSSSSLPLVTSATTSQETASSLPPATTTKTSEQTTLVTVTS 1240

  Fly  1329 EKPEDDTTVEDSTPIPEESTTIAQETTYDPEGSTTREDDTTVAIETTTEKPEDDTTVEDSTPIPE 1393
              .|.....|..:|      .|....|....|.|| |..|...|.||....:...|.|.:|...:
Yeast  1241 --CESHVCTESISP------AIVSTATVTVSGVTT-EYTTWCPISTTETTKQTKGTTEQTTETTK 1296

  Fly  1394 ESTTVAQDTTNDPEGSTTREEDTTVAIETTTEKPEDDTTVEDSTPIPEETTTVGQETTY----DP 1454
            ::|.|...:......|.|    .:.||.:|:....:..|.|.:|..|..||...|:||.    ..
Yeast  1297 QTTVVTISSCESDVCSKT----ASPAIVSTSTATINGVTTEYTTWCPISTTESRQQTTLVTVTSC 1357

  Fly  1455 EGSTTREDDTTVAIETTTEKPEDDTTVEDSTPIPEETTTVAQETTYDPEGSTTRDDT--TVAIET 1517
            |.....|..:...:.|.|....|..||. .|..|:   |..:|:......|.|.:.|  |:|.||
Yeast  1358 ESGVCSETASPAIVSTATATVNDVVTVY-PTWRPQ---TANEESVSSKMNSATGETTTNTLAAET 1418

  Fly  1518 TTEKPEDDT-----TAEGSTPI---------PDTSTTVNQDTTTDESSTV-VTTTNIPKESTTLG 1567
            ||.....:|     .||..|.:         .:|.|....|.....||.| |:.|...|..|:.|
Yeast  1419 TTNTVAAETITNTGAAETKTVVTSSLSRSNHAETQTASATDVIGHSSSVVSVSETGNTKSLTSSG 1483

  Fly  1568 DSTLSPGENSTAGQVSTSTTLVYDTTSSPIPSSSRS 1603
            .||:|....||    ..|:.:.|.|.|..|.:.:.|
Yeast  1484 LSTMSQQPRST----PASSMVGYSTASLEISTYAGS 1515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc68E	NP_996064.1	ChtBD2	<1761..1791	CDD:214696
		ChtBD2	1626..1668	CDD:214696
		ChtBD2	1688..1734	CDD:214696
FLO1	NP_009424.1	PA14	100..249	CDD:284994	13/73 (18%)
		Flocculin_t3	1235..1276	CDD:290639	11/49 (22%)
		Flocculin_t3	1303..1341	CDD:290639	9/41 (22%)
		Flocculin_t3	1349..1392	CDD:290639	11/46 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000