DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc68E and CG7252

DIOPT Version :9

Sequence 1:	NP_996064.1	Gene:	Muc68E / 2768990	FlyBaseID:	FBgn0053265	Length:	1799	Species:	Drosophila melanogaster
Sequence 2:	NP_648527.1	Gene:	CG7252 / 39353	FlyBaseID:	FBgn0036226	Length:	474	Species:	Drosophila melanogaster

Alignment Length:	415	Identity:	100/415 - (24%)
Similarity:	150/415 - (36%)	Gaps:	100/415 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1457 STTREDDTTVAIETTTEKPEDDTTVEDSTPIPEETTTVAQETTYDPEGSTTRDDTTVAIETTTEK 1521
            |...|.|.....:...|:.:|  .::|   |.|.||.|.::.  ||       |||    |:..:
  Fly    87 SAFAEVDDQCTCDCCAEECQD--PIDD---IDETTTAVTEDC--DP-------DTT----TSATE 133

  Fly  1522 PEDDT-TAEGSTPIPDTSTTVNQDTTTDESSTVV------TTTNIPKESTTLGDSTLSPG----- 1574
            |.|.| ..:.:|...|.:   |...||..|.:||      :.|:...:.|  |.....||
  Fly   134 PSDSTEPTDATTDFDDPN---NSSNTTPSSPSVVPSYCKSSRTDCVNQKT--GTYIDMPGICVRF 193

  Fly  1575 ---ENSTAGQVSTSTTLVYDTTSSP---------IPSSSRSTTLEPSSSSSPETTTSSLPPLSCS 1627
               .|..|.:....:.|.::|....         .|::..||.:|     .|..||.|.......
  Fly   194 IQCNNGCAEEFQCPSGLYFNTAIDDCDYWWNVDCTPTADGSTEIE-----GPSGTTCSSQGECAG 253

  Fly  1628 TGYQYLPHPTNCHKYIHCSNGHELIMECPANLYWDYHKFVCS---------GDSGV-CYND---- 1678
            ....|:....|.:.:..|.....:.|.|...|.::....||.         |.|.| ||.|
  Fly   254 KRDGYMIADPNSNGFFVCQCQCPIAMPCSEGLKFNETAQVCDWIKDTKSAIGSSAVQCYGDLVYN 318

  Fly  1679 --------TEN------SNPEEKVCGPGVDFLAHPTD--CTMYLQCSNGVALERKCPDPLYWNPE 1727
                    .||      .|....||....:....|.:  |.|:.:|:...|:|:.||:.|.:||.
  Fly   319 ATLDQCDYPENYVPKVECNTTSTVCQNQPEGELFPVEGKCNMFYKCNFNCAVEQYCPNNLVYNPN 383

  Fly  1728 IKSCDWSNKY-C-------TNLRASQS-ISCAA-----GMNFNVF---QSDCSKYVKCFGLRGVV 1775
            .:.|::...| |       :...|..| |:|.:     |.....:   .::||.||.|.....|.
  Fly   384 TEECEYPQDYVCPWEYTPPSGPNAGPSGIACESNGRCMGQREGTYLKSTTNCSNYVVCQCECEVE 448

  Fly  1776 MSCNSGLYWNPVSQVCE-KSRRFCT 1799
            |.|..||||:...|.|. |::..||
  Fly   449 MECADGLYWDESLQTCNYKNQVTCT 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc68E	NP_996064.1	ChtBD2	<1761..1791	CDD:214696	13/29 (45%)
		ChtBD2	1626..1668	CDD:214696	6/41 (15%)
		ChtBD2	1688..1734	CDD:214696	14/47 (30%)
CG7252	NP_648527.1	CBM_14	30..79	CDD:279884
		CBM_14	175..226	CDD:279884	8/52 (15%)
		CBM_14	251..296	CDD:279884	8/44 (18%)
		CBM_14	343..394	CDD:279884	13/50 (26%)
		CBM_14	420..471	CDD:279884	16/50 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33909at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020