DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc68E and CG31077

DIOPT Version :9

Sequence 1:	NP_996064.1	Gene:	Muc68E / 2768990	FlyBaseID:	FBgn0053265	Length:	1799	Species:	Drosophila melanogaster
Sequence 2:	NP_733185.2	Gene:	CG31077 / 318583	FlyBaseID:	FBgn0051077	Length:	988	Species:	Drosophila melanogaster

Alignment Length:	665	Identity:	143/665 - (21%)
Similarity:	218/665 - (32%)	Gaps:	190/665 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1249 EESTTVAQDTTNDPEGSTTREDDTTVAIDTTTEKPEDDTTVEDSTPIPEESTTVAQDTTNDPEGS 1313
            :||||          .::.::.::|.|...:|:....:.|.::|.........|.|.|. ..||.
  Fly   382 DESTT----------PNSYQQTESTDADFQSTDSALQEVTSQNSCIFDLNGACVGQSTI-CTEGK 435

  Fly  1314 TTREDDTTVAIDTTTEKPEDDTTVEDSTPIPEESTTIAQETTYDPEGSTTREDD-------TTVA 1371
            ..|:.:.....    .|..|...||:..|         :.|.||....|...|:       |::.
  Fly   436 KQRDINNCAGY----LKCIDGEFVEEECP---------ESTYYDSNLETCLVDNYGACVTSTSIC 487

  Fly  1372 IETTTEKPEDDTT---------VE-------------------DSTPIPEESTTVAQDTTNDPEG 1408
            :|...|:...|..         ||                   |...:..:|:.|  |...|.|.
  Fly   488 VEGIVEEDPKDCAGYNQCVRGKVEPLKCAFGRYFNGTQGECLIDLDEVCAKSSQV--DYDRDLEQ 550

  Fly  1409 STTREEDTTVAIETTTEKPEDDTTVED-STPIPEETTTVGQETTYDPEGSTTREDDTTVAIETTT 1472
            ....:..:...:|.|    ..|||:.| ||     .::......|....|.|..:.||..:.|:|
  Fly   551 FQYSQSTSEYLLEYT----NTDTTIADFST-----ESSNADFNRYTDSNSYTDTESTTNDVPTST 606

  Fly  1473 EKPEDDTTVEDSTPIPEETTTVAQETTYDPEGSTTRDDTTVAIETTTE-KPED------------ 1524
            |....|.   .:|.:..:.||:......|....|...:.|:.||...| .|:|
  Fly   607 EVSTFDL---KTTDLSLQFTTLDGVDNLDINTGTCVYNNTLFIEGIREVNPQDCAGYIECFGGVA 668

  Fly  1525 ------------DTTAEGSTPIPD-----TSTTVNQDTTTDESSTVVTTTNIPKESTTLGDSTLS 1572
                        :|....|..:.:     ..|.|....||.||:...||:..|......|...|.
  Fly   669 KELKCDSGRYFNETQRNCSVDVDEICLKSDKTIVLDLQTTTESTPNFTTSVDPFAKCRDGQLRLD 733

  Fly  1573 PGENSTAG----------QVSTSTTLVYDTTSSPIPSSSRSTTLEPSSSSSPETTTSSLPPLSCS 1627
            |  .:.||          :....:...|::|||......|:|                     |.
  Fly   734 P--KNCAGFLKCVDGELKEEMCPSGFFYNSTSSKCMVDIRAT---------------------CV 775

  Fly  1628 TGYQYL------PHPTNCHKYIHCSNGHELIMECPANLYW---------DYHKFVCS------GD 1671
            |..:|.      ..|.||..|..|..|....:.||...|:         |.|| ||:      ..
  Fly   776 TNIKYCIEGVREEDPNNCAGYRQCIRGLVQNLNCPLGQYFNVAERDCLMDVHK-VCARTEEVYKS 839

  Fly  1672 SGVCYNDT--ENSNPEEK----VCGPGVDFLA---------HPTDCTMYLQCSNGVALERKCPDP 1721
            ..|.:|||  ..:.|:|.    :.|..||.||         .|.:|..||:|.||..:|..||:.
  Fly   840 DEVQHNDTGPPMTKPDESCIRDINGVCVDPLAKCREGQHKLDPNNCAGYLKCQNGELIEELCPNG 904

  Fly  1722 LYWNPEIKSC--DWSNKYCTNLRASQSISCAAGMNFNVFQSDCSKYVKCFGLRGVVMSCNSGLYW 1784
            .|::..:|.|  |......||::.     |..|. ......||:.|.:|...:...:.|..|.|:
  Fly   905 FYYDFLMKICLVDRRGICVTNIQI-----CDEGA-LEEDPHDCAGYRQCIDGQVENLKCPFGTYF 963

  Fly  1785 N--------PVSQVC 1791
            |        .|.::|
  Fly   964 NVPLRDCLIDVDEIC 978

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc68E	NP_996064.1	ChtBD2	<1761..1791	CDD:214696	9/37 (24%)
		ChtBD2	1626..1668	CDD:214696	15/56 (27%)
		ChtBD2	1688..1734	CDD:214696	19/56 (34%)
CG31077	NP_733185.2	CBM_14	43..81	CDD:279884
		ChtBD2	<212..245	CDD:214696
		CBM_14	267..308	CDD:279884
		CBM_14	439..472	CDD:279884	8/45 (18%)
		CBM_14	733..769	CDD:279884	7/37 (19%)
		CBM_14	881..914	CDD:279884	12/32 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33909at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020