Protein Alignment Muc68E and Impg2

DIOPT Version :9

• Sequence 1: NP_996064.1
• Gene: Muc68E / 2768990
• FlyBaseID: FBgn0053265
• Length: 1799
• Species: Drosophila melanogaster
• Sequence 2: XP_017172459.1
• Gene: Impg2 / 224224
• MGIID: 3044955
• Length: 1247
• Species: Mus musculus
• Alignment Length: 1072
• Identity: 207/1072 - (19%)
• Similarity: 368/1072 - (34%)
• Gaps: 278/1072 - (25%)

  Fly   898 KREDDTTVEDSTPIPEESTTVAQDTTNDPEGSTTREEDTTVAIETTTEKPE-------DDTTVED 955
            :..:.::.:|.:..||.|..|....|:...|:.:......:|.|::...|:       ::.|.|.
Mouse   132 REAESSSCKDQSCGPELSFPVPIGETSTLTGAVSSASYPGLASESSAASPQESISNEIENVTEEP 196

  Fly   956 STPIPEETTTVG--------QETTYDPEGSTTR---EDDTTVAIDTTTEKP-------------- 995
            :.|..|:.....        .|...||..:..|   |:..:......|..|
Mouse   197 TQPAAEQIAEFSIQLLGKRYSEELRDPSSALYRLLVEEFISEVEKAFTGLPGYKGIRVLEFRAPE 261

  Fly   996 EDDTTVEDSTPIPEESTTVAQDT-------TNDPEGSTTRE-DDTTVAI-------DTTTEKPED 1045
            |:|:.::....:......::..|       :|..|.....| ||...|:       |...|....
Mouse   262 ENDSGIDVHYAVTFNGEAISNTTWDLISLHSNKVENHGLVEMDDKPTAVYTISNFRDYIAETLHQ 326

  Fly  1046 DTTVEDST--PIPEESTTIAQETTYDPEGSTTREDDTTVAIETTTEKPEDDTTVEDSTPIPEEST 1108
            :..:.:|:  |.|:....|.......|:......:..:.:::.||....|:|...:..   ...|
Mouse   327 NFLMGNSSLNPDPKSLQLINVRGVLLPQTEDIVWNTQSSSLQVTTSSILDNTLQAEWL---SADT 388

  Fly  1109 TVAQDTTNDPEG-------STTREDDTTVAID--TTTEKPEDDTTVEDSTPIPEESTTVAQDTTN 1164
            |....||..|.|       :|.||..:..|:.  .:|.|....|.|..|: :||..
Mouse   389 TTTTTTTISPFGFSSSSPSATGRELQSQSALRDVVSTSKLASPTKVVLSS-LPEIL--------- 443

  Fly  1165 DPEGSTTREEDTTVAIETTTEKPEDDTTVEDSTPIPEETTTVGQETTYDPEGSTTREDDTTVAID 1229
              .||:......|.|:            ::...|:..|..|.|.....|...||...:||  :||
Mouse   444 --GGSSLTLHSVTPAV------------LQPDLPVAPEGRTSGSFILEDGLASTEELEDT--SID 492

  Fly  1230 TTTEKPEDDTTVEDSTPIPEESTTVAQDTTNDPEGSTTREDDTTVAIDTTTEKPEDDTTVEDSTP 1294
            .....|......:::.|..|:|.|....|   |..:::..:|.|..|.|.:......:.:.|...
Mouse   493 GLPSSPLIQPVPKETVPPMEDSDTALLST---PHLTSSAIEDLTKDIGTPSGLESLASNISDQLE 554

  Fly  1295 I----PEESTTVAQDTTNDPE-GSTTREDDTTVAIDTTTEKPEDDTTVEDSTPIPEESTTIAQET 1354
            :    |:  |:|.:|...:.. ||.:.:|...:      :.|..:|::|.:|....:|.:..|:.
Mouse   555 VIPWFPD--TSVEKDFIFESGLGSGSGKDVDVI------DWPWSETSLEKTTKPLSKSWSEEQDA 611

  Fly  1355 TYDPEGSTT-----REDDTTVAIETTT----EKP----EDDTTVEDSTPIPEESTT------VAQ 1400
            ....||...     |.|.|...||::.    ::|    |:::.|..:.||..||.|      .::
Mouse   612 LLPTEGREKLHIDGRVDSTEQIIESSEHRYGDRPIHFIEEESHVRSTIPIFVESATPPTSPIFSK 676

  Fly  1401 DTTNDPE---GSTTREE--DTTVAIETTTEKPEDDTTVEDSTPIPEETTTVGQETTYDPEGSTTR 1460
            .|::.|:   .|.|:..  ..|:||..:|:|                |..|.:|.....|.|:.:
Mouse   677 HTSDVPDIDSYSLTKPPFLPVTIAIPASTKK----------------TDEVLKEDMVHTESSSHK 725

  Fly  1461 EDDTTVAIETTTEKPEDDTTVEDSTPIPEETTTVAQETTYDPEGSTTRDDTTVAIETTTEKPEDD 1525
            |.|:.|.:.....:|.       .|.:||..|...:.::.   |..:| ||..:...:|::....
Mouse   726 ELDSEVPVSRPDMQPV-------WTMLPESDTVWTRTSSL---GKLSR-DTLASTPESTDRLWLK 779

  Fly  1526 TTAEGSTPIPDTSTTVNQDTTTDESSTVVTTTNIPKESTTLG----DSTLSPGENSTA-GQVSTS 1585
            .:...||.:|.|:     .:|..|...::...:|..|...:|    .|.|:..::..| ..|..|
Mouse   780 ASMTQSTELPSTT-----HSTQLEEEVIMAVQDISLELDQVGTDYYQSELTEEQHGKADSYVEMS 839

  Fly  1586 TTLVYDTTSSPIPS-SSRSTTLEPSSSSSPETTTSSL---------------------------- 1621
            |::.|  |..||.: .::...|..:.::.......||
Mouse   840 TSVHY--TEMPIVALPTKGGVLSHTQTAGALVVFFSLRVTNMLFSEDLFNKNSLEYKALEQRFLE 902

  Fly  1622 ---PPLSCS-TGYQYL--------------------PHPTNCHKYIH------CSNGHELIMECP 1656
               |.|..: :|:|.|                    ..|.|.:|.::      |:..::.:
Mouse   903 LLVPYLQSNLSGFQNLEILSFRNGSIVVNSRVRFAESAPPNVNKAMYRILEDFCTTAYQTM---- 963

  Fly  1657 ANLYWDYHKFVCSGDSGVCYNDTENSNPEEKVCGPGVDFLAHPTDCTMYLQC-SNGVALERKCP- 1719
             ||  |..|:....:||      :.:||    |    .|.|    |..:.:| .|..:.|.||.
Mouse   964 -NL--DIDKYSLDVESG------DEANP----C----KFQA----CNEFSECLVNPWSGEAKCKC 1007

  Fly  1720 DPLYWN----PEIKSCDWSNKYCTN-----LRASQSISCAAGM--------NFNVFQSDCSK--- 1764
            .|.|.:    |....||....:|.|     :.......|...:        ::::|:|..|.
Mouse  1008 YPGYLSVDELPCQSLCDLQPDFCLNDGKCDIMPGHGAICRTQILVFHKSTKSYHLFKSHLSSPWT 1072

  Fly  1765 ---YVKCFGLRGVVMSCNSGLYWNPVSQVCEK 1793
               ...||...   :.|..|..|....|.||:
Mouse  1073 LLVMTLCFLYH---IECRVGSNWWYRGQHCEE 1101

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc68E	NP_996064.1	ChtBD2	<1761..1791	CDD:214696	7/35 (20%)
		ChtBD2	1626..1668	CDD:214696	11/68 (16%)
		ChtBD2	1688..1734	CDD:214696	14/51 (27%)
Impg2	XP_017172459.1	SEA	201..311	CDD:382994	17/109 (16%)
		SEA	862..984	CDD:214554	20/142 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000