DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc68E and cpg-2

DIOPT Version :9

Sequence 1:	NP_996064.1	Gene:	Muc68E / 2768990	FlyBaseID:	FBgn0053265	Length:	1799	Species:	Drosophila melanogaster
Sequence 2:	NP_498551.3	Gene:	cpg-2 / 175991	WormBaseID:	WBGene00015102	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	317	Identity:	68/317 - (21%)
Similarity:	99/317 - (31%)	Gaps:	99/317 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1525 DTTAEGSTPIPDTSTTVNQDTTTDESSTVVTTTNIPKESTTLGDSTLSPGENSTAGQVSTSTTLV 1589
            :|:.|||......::.......:.|.|         .|::..|....| ||.|.:|:.:....
Worm    85 ETSGEGSGESSGEASGEGSGEASGEGS---------GEASGEGSGEAS-GEGSGSGEETVENV-- 137

  Fly  1590 YDTTSSPIPSSSRSTTLEPSSSSSPETTTSSLPPLSCSTGYQYLPHPTNCHKYIHCSNGHELIME 1654
                         ...||..:.||...||                      .|..|:......:.
Worm   138 -------------CENLEDGAYSSGGCTT----------------------YYFFCTTNTARFLS 167

  Fly  1655 CPANLYWDYHKFVC----------------------------------SGD-SGVCYNDT----- 1679
            ||..|::|.....|                                  ||: ||....::
Worm   168 CPTPLFYDADSQKCIWKSLVEECKEDLTITDGSGETSGEGSGEASGEASGEGSGEASGESSGQGS 232

  Fly  1680 -----ENSNPEEKVCGPGVDFLAHPTD-C-TMYLQCSNGVALERKCPDPLYWNPEIKSCDWSNKY 1737
                 |.|...|..|....|.: ||.. | |.:|.||.|:|....||..|.:||.|..|||....
Worm   233 GEASGEGSGELEPTCEGKADGI-HPNGVCSTNFLTCSGGIARIMDCPASLVFNPTILVCDWPRDV 296

  Fly  1738 --CTNLRASQSISCAAGMNFNVFQSDCSKYVKCFGLRGVVMSCNSGLYWNPVSQVCE 1792
              |..|...|. :|.....|: |....|.:..|...|.:||.|.:||.::..:..|:
Worm   297 AECAGLPTPQP-TCEEDGYFS-FGQCSSSFTACTNGRAIVMFCPAGLKFSESTVRCD 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc68E	NP_996064.1	ChtBD2	<1761..1791	CDD:214696	8/29 (28%)
		ChtBD2	1626..1668	CDD:214696	6/41 (15%)
		ChtBD2	1688..1734	CDD:214696	19/47 (40%)
cpg-2	NP_498551.3	CBM_14	24..76	CDD:279884
		CBM_14	138..190	CDD:279884	13/73 (18%)
		ChtBD2	245..293	CDD:214696	19/48 (40%)
		CBM_14	311..359	CDD:279884	11/42 (26%)
		CBM_14	403..454	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010