DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc68E and R02F2.4

DIOPT Version :9

Sequence 1:	NP_996064.1	Gene:	Muc68E / 2768990	FlyBaseID:	FBgn0053265	Length:	1799	Species:	Drosophila melanogaster
Sequence 2:	NP_498171.1	Gene:	R02F2.4 / 175755	WormBaseID:	WBGene00019833	Length:	431	Species:	Caenorhabditis elegans

Alignment Length:	369	Identity:	71/369 - (19%)
Similarity:	129/369 - (34%)	Gaps:	104/369 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1447 GQETTYDPEGSTTREDDTTVAIETTTEKPEDDTTVEDSTPIPEETTTVAQETTY-DPEGSTTRDD 1510
            |:|..:..:||.....|                                :|.|: |..|.::.|:
Worm    81 GEENEFSGDGSGESSGD--------------------------------EEITFGDSSGESSGDE 113

  Fly  1511 TTVAIETTTEKPEDDTTAEGSTPIPDTSTTVNQDTTTDESSTVVTTTNIPKESTTLGDSTLSPGE 1575
               .:|...|..:|...:.|                |..||.::..:..|:
Worm   114 ---LLENVCESLKDGVYSSG----------------TCSSSYIICNSGSPR-------------- 145

  Fly  1576 NSTAGQVSTSTTLVYDTTSSPIPSSSRSTTLEPSSSSSPETTTS--SLPPLSCSTGYQYLPHPTN 1638
                 .:|.||.|:||.|:.   ..|....::..|..|.|...|  ::....||
Worm   146 -----FLSCSTPLIYDPTNK---KCSWKGMIDECSQVSGEYCESDGNISKSECS----------- 191

  Fly  1639 CHKYIHCSNGHELIMECPANLYWDYHKFVCSGDSGVCYNDTENSNPEEKVCGPGVDFLAHPTDCT 1703
             :.:..||.|......|||||.::.....|.....|.....::..|:.  ||....:.:.....:
Worm   192 -NVFFSCSEGIAHRRNCPANLVFNPAISSCDWPKNVMDCSEKSEKPQN--CGEVDGYFSFGRCSS 253

  Fly  1704 MYLQCSNGVALERKCPDPLYWNPEIKSCDW----------SNKYCTNLRASQSISCAAGMNFNVF 1758
            .:..|:||:.:...|||.|.::.:.:.||:          |:.:..|.:||::::....|:..::
Worm   254 SFSACTNGIPIVMFCPDGLMFSEKNQMCDYEWNVDECDLESSGFMENYKASEALTPCTNMDNGLY 318

  Fly  1759 QSDCS-KYVKCFGLRGVVMSCNSGLYWNPVSQVC---EKSRRFC 1798
            ..||: :.:.|...|..:..|...|.:|..|.:|   |.|.:.|
Worm   319 ALDCTPRVLSCQNGRENIFECPPSLVFNENSLICDYPETSLKCC 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc68E	NP_996064.1	ChtBD2	<1761..1791	CDD:214696	8/30 (27%)
		ChtBD2	1626..1668	CDD:214696	10/41 (24%)
		ChtBD2	1688..1734	CDD:214696	11/55 (20%)
R02F2.4	NP_498171.1	CBM_14	25..74	CDD:279884
		ChtBD2	117..165	CDD:214696	15/85 (18%)
		CBM_14	185..229	CDD:279884	12/55 (22%)
		ChtBD2	240..283	CDD:214696	9/42 (21%)
		CBM_14	310..361	CDD:279884	12/50 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920