DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc68E and si:ch211-286b4.4

DIOPT Version :9

Sequence 1:	NP_996064.1	Gene:	Muc68E / 2768990	FlyBaseID:	FBgn0053265	Length:	1799	Species:	Drosophila melanogaster
Sequence 2:	XP_021322239.1	Gene:	si:ch211-286b4.4 / 100005359	ZFINID:	ZDB-GENE-131127-605	Length:	2996	Species:	Danio rerio

Alignment Length:	474	Identity:	98/474 - (20%)
Similarity:	133/474 - (28%)	Gaps:	173/474 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly  1383 TTVEDSTPIPEESTTVAQDTTNDPEGSTTREEDTTVAIETTTEKPEDDTTVEDSTPIPEETTTVG 1447
            |:..|.:..|......|..:| .|.||...........:|:  :|:               .|:.
Zfish   466 TSFNDCSSCPPSRYCAAPGST-QPSGSCAPGHYCVKGADTS--RPQ---------------ATLS 512

  Fly  1448 QETTY---DPEGSTTRED------DTTVAIETTTEKPEDDTTVEDSTPIP----EETTTVAQETT 1499
            |:|.:   .|.....:.|      :.|.||..    |.|.....|..|.|    |....:.:..|
Zfish   513 QQTCFCDLIPSSHLQKYDLCHLKHNITCAIHI----PGDGAVWTDLDPRPLLESEAPLQIREPCT 573

  Fly  1500 -----------YDPEGSTTRDDTTVAIETTTEKPEDDTTAEGSTPIP-DTSTTVNQDTTTDESST 1552
                       |.|.||                         |.|.| |:.:..||.........
Zfish   574 GFKGDLCPTGSYCPVGS-------------------------SVPQPCDSGSYCNQTGLYTPVGL 613

  Fly  1553 VVTTTNIPKESTTLGDSTLSPGENSTAGQVSTSTTLVYDTTSSPIPSSSRSTTLEPSSSSSPETT 1617
            .......|..|:........||.              |....:|.|.|....|:..|:..|....
Zfish   614 CFAGFFCPTGSSNPSAVLCPPGH--------------YCPQGTPRPLSCPQGTVRSSAGGSSAGD 664

  Fly  1618 TSSLPP--------LS-----CSTGYQYLPHPTNCHK---YIHCSNGH----ELIMECPANLYWD 1662
            ....||        |:     ||.|| |.|...|..:   |: |..||    .:|||.|
Zfish   665 CLECPPGYFCEQRGLTEPSGLCSEGY-YCPGGQNTSRPAEYV-CRAGHFCQRGIIMERP------ 721

  Fly  1663 YHKFVCSGDSGVCYNDTENSNPEEKVCG--PGVDF-----LAHPTDCTMYLQCSNGVALERKCPD 1720
                        |:..|...:|.:..|.  |...|     :.||..|.....|..|.:.:..||.
Zfish   722 ------------CFPGTFQPSPGQHRCDVCPARFFCPEHGMTHPFPCQPGYYCPVGASNQHPCPP 774

  Fly  1721 PLYWN-------PEIKSCDWSNKYCTNLRASQSIS----CAAGMNFNVFQSDCSKYVKCFGLRGV 1774
            ..:.|       .|...|| ...||   ..|.::|    |:||.             .|||  |.
Zfish   775 GGFGNRSGLADSSECSQCD-PGTYC---MGSGNVSPTGPCSAGF-------------LCFG--GA 820

  Fly  1775 VMS----------CNSGLY 1783
            |:|          |.||.|
Zfish   821 VLSSPNDNETGMLCPSGFY 839

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc68E	NP_996064.1	ChtBD2	<1761..1791	CDD:214696	10/33 (30%)
		ChtBD2	1626..1668	CDD:214696	15/48 (31%)
		ChtBD2	1688..1734	CDD:214696	14/59 (24%)
si:ch211-286b4.4	XP_021322239.1	Ephrin_rec_like	<945..983	CDD:311571
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010