Protein Alignment ppk5 and ASIC3

DIOPT Version :9

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_064717.1
• Gene: ASIC3 / 9311
• HGNCID: 101
• Length: 549
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 98/500 - (19%)
• Similarity: 172/500 - (34%)
• Gaps: 156/500 - (31%)

  Fly    26 ALVLFVAVNL-----AVGIYNKWDSTPVIIGISSKMTPIDQ-----IPFPTITVCNMNQAKKSKV 80
            |:||.||..|     .|..|.::          ...|.:|:     :.||.:|:||:|..::|:
Human    48 AVVLSVATFLYQVAERVRYYREF----------HHQTALDERESHRLIFPAVTLCNINPLRRSR- 101

  Fly    81 EHLMPGSIRYAMLQKTCYKESNFSQYMDTQHRNETFSNFI----LDVSEKCA-------DLIVSC 134
              |.|..:.:|.........:..:.::....|......|:    .|:::..|       |:::.|
Human   102 --LTPNDLHWAGSALLGLDPAEHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDC 164

  Fly   135 IFHQQRIPC-TDIFRETFVDEGLCCIFNVLHPYYLYKFKSPYIRDFTSSDRFADIAVDWDPISGY 198
            .|..|  || .:.|...|...|.|..||                   |....|::...
Human   165 RFRGQ--PCGPENFTTIFTRMGKCYTFN-------------------SGADGAELLTT------- 201

  Fly   199 PQRLPSSYYPRPGVGVGTSMGLQIVLNGHVDDYFCSSTNGQ------GFKILLYNPIDQPRMKES 257
                     .|.|:|    .||.|:|:...::|.....:.:      |.::.:::..:.|.:.:.
Human   202 ---------TRGGMG----NGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQL 253

  Fly   258 GLPVMIGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQELLFY--------------RY--- 305
            ||.|..|:||                        .:...:|:|.|.              .|
Human   254 GLGVSPGYQT------------------------FVSCQQQQLSFLPPPWGDCSSASLNPNYEPE 294

  Fly   306 ---------------YTRRNCEAECDSMFFLRLCSCIPYYLPLIYPNASVCDVFHFE-CLNRAES 354
                           ||...|...|::.:..|.|.|...|:|...|   ||....:: |.:.|..
Human   295 PSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVP---VCSPQQYKNCAHPAID 356

  Fly   355 QIFDLQSSQCKEFCLTSCH----DLIFFPDAFSTPFSQKDVKAQTNYLTNFSSEYMRKN-LAVVN 414
            .:....|..|...|.::.:    .::..|...:..|..:.:        |.|..|:.:| ||:..
Human   357 AMLRKDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKL--------NRSEAYIAENVLALDI 413

  Fly   415 FFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIGFSVIFLAEII 459
            ||...||.....:.:|. .:|.:...||.|.|.||.|::.:.||:
Human   414 FFEALNYETVEQKKAYE-MSELLGDIGGQMGLFIGASLLTILEIL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:279230	98/499 (20%)
ASIC3	NP_064717.1	ASC	20..534	CDD:295594	98/499 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..307		1/21 (5%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152165
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.750