Protein Alignment ppk5 and asic1b

DIOPT Version :10

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_999956.1
• Gene: asic1b / 407672
• ZFINID: ZDB-GENE-040513-1
• Length: 557
• Species: Danio rerio
• Alignment Length: 490
• Identity: 102/490 - (20%)
• Similarity: 183/490 - (37%)
• Gaps: 125/490 - (25%)

  Fly     8 ISDNNYS-----WWIKLYFAIIFALVLFVAVNLAVGIYNKWDSTPVIIGISSKMTPIDQIPFPTI 67
            :.|..:|     |  .|.|.:..::.|...|:..: .|.::|...::...::|     .:.||.|
Zfish    83 VEDKKFSIRQGLW--ALVFLLAISMFLLQVVDRVI-YYLQYDYVTLLDERNAK-----NMTFPAI 139

  Fly    68 TVCNMNQAKKSKVEH----LMPGSIRYAMLQKTCYKESNFSQYM------DTQHRNETFSNFILD 122
            |:||.|..::|::.:    .|...:.|         |.|.:..:      |.|....:.:.|...
Zfish   140 TLCNYNTFRRSQLSYSDLLFMGPLLGY---------EDNMAPGIPLAPEPDRQGSRFSLAEFFNR 195

  Fly   123 VSEKCADLIVSCIFHQQRIPC-TDIFRETFVDEGLCCIFNVLHPYYLYKFKSPYIRDFTSSDRFA 186
            ...:..|:::.|.|..:.  | .:.:||.|...|.|..||
Zfish   196 TRHRMDDMLLECNFAGKE--CGAEHWREIFTRYGKCYTFN------------------------- 233

  Fly   187 DIAVDWDPISGYPQRLPSSYYPRPGVGVGTSMGLQIVLNGHVDDYF------CSSTNGQGFKILL 245
                     ||...| |.....:.|:|    .||:|:|:...|:|.      ..:|...|.|:.:
Zfish   234 ---------SGQDGR-PLLITTKGGMG----NGLEIMLDIQQDEYLPVWGETDETTFEAGIKVQI 284

  Fly   246 YNPIDQPRMKESGLPVMIGHQTSFRIIARNV----------EATPSIRNIHRTKRQCIFSDEQEL 300
            :...:.|.:.:.|..|..|.||......:.:          :|||            |.||
Zfish   285 HTQDEPPFIDQLGFGVAPGFQTFVSCQEQRLTYLPPPWGDCKATP------------IDSD---- 333

  Fly   301 LFYRYYTRRNCEAECDSMFFLRLCSCIPYYLPLIYPNASVCDVFHF-ECLNRAESQIFDLQSSQC 364
             |:..|:...|..:|::.:.:..|:|...::|   .:|..|....: ||.:.|...:.:..:..|
Zfish   334 -FFNTYSITACRIDCETRYLVENCNCRMVHMP---GDAPYCTPEQYKECADPALDFLVERDNDYC 394

  Fly   365 KEFCLTSCHDLIFFPDAFSTPFSQKDVKAQTNYLT---NFSSEYMRKNLAVVN-FFHTDNYFRSS 425
              .|.|.|:...:..:   ..|.:...||...||.   |.:.:|:..|:.|:: ||...||....
Zfish   395 --VCETPCNMTRYGKE---LSFVRIPSKASAKYLAKKYNKTEQYISDNIMVLDIFFEALNYETIE 454

  Fly   426 VRTSY--TGPTEYMASTGGIMSLMIGFSVIFLAEI 458
            .:.:|  .|   .:...||.|.|.||.|::.:.|:
Zfish   455 QKKAYELAG---LLGDIGGQMGLFIGASILTILEL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:459966	102/490 (21%)
asic1b	NP_999956.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..57
		ENaC	66..548	CDD:273304	102/490 (21%)
		GAS motif, ion selectivity filter. /evidence=ECO:0000250|UniProtKB:Q1XA76	477..479		1/1 (100%)