Protein Alignment ppk5 and asic2

DIOPT Version :9

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_005164179.1
• Gene: asic2 / 407669
• ZFINID: ZDB-GENE-040513-4
• Length: 564
• Species: Danio rerio
• Alignment Length: 528
• Identity: 97/528 - (18%)
• Similarity: 190/528 - (35%)
• Gaps: 143/528 - (27%)

  Fly     4 LKYVISDNNYSWWIKLYFAIIFALVLFVAVNLAVGIYNKWDSTPVIIGISSKMTPIDQIPFPTIT 68
            |:::.|.:| |...:.::.|.|...|.:.::.:......|.:.|....:.::..  .::.|||:|
Zfish    76 LRHICSPSN-SLSRRAFWMIAFCTCLGLLLSWSSNRLLHWLAFPTHTRVHTEWA--KELAFPTVT 137

  Fly    69 VCNMNQAKKSKVEHLMPGSIRYA-------MLQKTC----------------YKESNFSQYMDTQ 110
            :||.|..   ::.||....:.:|       :..:|.                .|.|:|..::..:
Zfish   138 ICNNNPV---RLYHLTKSDLYFAGHWLGLLLANRTARPLVLDLLQDDRRGWFSKLSDFRLFLPPR 199

  Fly   111 HRNETFSNFILDVSEKCADLIVSCIFHQQRIPC-TDIFRETFVDEGLCCIFNVLHPYYLYKFKSP 174
            ....|...|:..:..:..|::::|.:..:  || ...|...|...|.|.:||.
Zfish   200 RFEGTSLEFMDRLGHQLEDMLLACKYRGE--PCGAHNFSTVFTRYGKCYMFNA------------ 250

  Fly   175 YIRDFTSSDRFADIAVDWDPISGYPQRLPSSYYPRPGVGVGTSMGLQIVLNGHVDDYFC------ 233
                          |.:...:             |..:..||..||:|:|:...|:|..
Zfish   251 --------------AEEGKTL-------------RTTMKGGTGNGLEIMLDIQQDEYLPVWGETE 288

  Fly   234 SSTNGQGFKILLYNPIDQPRMKESGLPVMIGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQ 298
            .:....|.::.:::..:.|.:.|.|..|..|.||                        .:.:.||
Zfish   289 ETAFEAGVRVQIHSQAEPPFVHELGFGVAPGFQT------------------------FVATQEQ 329

  Fly   299 ELLF-----------------YRYYTRRNCEAECDSMFFLRLCSCIPYYLPLIYPNASVCDVFHF 346
            .|.:                 ::.|:...|..||::.:.:..|:|...|:|   .::..|....:
Zfish   330 RLTYLPPPWGECVSRALDSGLFQVYSVSACRIECETRYIVENCNCRMVYMP---GDSPYCTPEQY 391

  Fly   347 -ECLNRAESQIFDLQSSQCKEFCLTSCH--------DLIFFPDAFSTPFSQKDVKAQTNYLTNFS 402
             :|...|.:.:..::.:.|  .|.:.|:        .::..|...|..:.:|..        |.|
Zfish   392 KDCAEPALAALSAVEGTNC--ICRSPCNMTRYNKELSMVKIPSKTSARYLEKKF--------NRS 446

  Fly   403 SEYMRKNLAVVN-FFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIGFSVIFLAEII-YIILFV 465
            .:|:..|:.|:: ||...||.....:.:|. ....:...||.|.|.||.|::.|.|:. |....|
Zfish   447 EKYITDNILVLDVFFEALNYETIEQKKAYE-VAGLLGDIGGQMGLFIGASILTLLELFDYAYEVV 510

  Fly   466 STLLLILI 473
            ...||.|:
Zfish   511 KERLLDLL 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:279230	92/513 (18%)
asic2	XP_005164179.1	ASC	71..538	CDD:295594	97/528 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586627
Domainoid	1	1.000	101	1.000	Domainoid score	I6864
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4956
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.900