DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk5 and ppk28

DIOPT Version :9

Sequence 1:	NP_996138.2	Gene:	ppk5 / 2768987	FlyBaseID:	FBgn0053289	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_573169.2	Gene:	ppk28 / 32671	FlyBaseID:	FBgn0030795	Length:	606	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	156/466 - (33%)
Similarity:	260/466 - (55%)	Gaps:	14/466 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LKYVISDNNYSWWIKLYFAIIFALVLFVAVNLAVGIYNKWDSTPVIIGISSKMTPIDQIPFPTIT 68
            ||| |::.:.:...:::|.:.|.||:.::|.....:|.||.::|:||..|:|......:|||.||
  Fly    52 LKY-IAEESITIPERIFFGLAFVLVVILSVFFISNVYVKWSASPIIISTSAKQKLTSNMPFPAIT 115

  Fly    69 VCNMNQAKKSKVEHLMPGSIRYAMLQKTCYKESNFS-QYMDTQHRNETFSNFILDVSEKCADLIV 132
            :||:|||..|||:.:...|..:::|...|.:..:.: .|:.|.   :.|...::||::.|..:::
  Fly   116 ICNLNQALLSKVDRIGRTSTNFSLLMGLCDQGGDTTISYIGTW---KYFKAILVDVAQPCEKMLL 177

  Fly   133 SCIFHQQRIPCTDIFRETFVDEGLCCIFNVLHPYYLYKFKSPYIRDFTSSDRFADIAVDWDPISG 197
            .|.|..:...|:.:|.....|:||||.||.|||.||.:..|..:|..|:........:||.|..|
  Fly   178 YCSFGSREEDCSWLFTSILTDDGLCCNFNALHPSYLIRNYSDDVRLETAHPNTRYELIDWTPEKG 242

  Fly   198 YPQRLPSSYYPRPGVGVGTSMGLQIVLNGHVDDYFCSSTNGQGFKILLYNPIDQPRMKESGLPVM 262
            |.:.||..|:||...|.|..|||.:|||..:.:|:|:.:...|||:|::||.:.|::...|..|.
  Fly   243 YARNLPEFYFPRTSGGTGIRMGLTVVLNASIAEYYCTKSMSVGFKVLVHNPAELPKVSNYGFVVT 307

  Fly   263 IGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQELLFYRYYTRRNCEAECDSMFFLRLCSCI 327
            .|.:....|.....:|.|:||:|.::.|:|:||||.:|.:||.|:|:|||.||::...||.|||:
  Fly   308 AGREARIPIEPVYEDALPTIRSIKKSVRRCLFSDENDLAYYRTYSRKNCELECEAKLLLRECSCV 372

  Fly   328 PYYLPLIYPNASVCDVFHFECLNRAESQIFDLQSSQCKEFCLTSCHDLIFFPDAFSTPFSQKDVK 392
            .||||.|.|.|.||.....:|.:|.:::|....::...|.|...|.:|. :....||.....|.:
  Fly   373 LYYLPRIDPLARVCGPNDNQCTDRVQTEIESSLTNLSCENCWPGCFELT-YRATLSTASIVSDPR 436

  Fly   393 AQT-----NYLTNFSSEYMR-KNLAVVNFFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIGFS 451
            .|.     .|:  |...|.. ..:::::|::..|.|||:.::...|.||::::|||::.|.:|||
  Fly   437 FQAGENLPEYI--FHGPYSNASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTGGLLGLFMGFS 499

  Fly   452 VIFLAEIIYII 462
            :..:.||.:.|
  Fly   500 IFSVIEIFFYI 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:279230	155/462 (34%)
ppk28	NP_573169.2	ASC	43..509	CDD:279230	155/463 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469312
Domainoid	1	1.000	101	1.000	Domainoid score	I6864
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4956
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D112386at6656
OrthoFinder	1	1.000	-	-		FOG0000867
OrthoInspector	1	1.000	-	-		mtm8412
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	11	10.800