Protein Alignment ppk5 and Scnn1a

DIOPT Version :10

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_113736.1
• Gene: Scnn1a / 25122
• RGDID: 3639
• Length: 699
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 114/610 - (18%)
• Similarity: 197/610 - (32%)
• Gaps: 230/610 - (37%)

  Fly     4 LKYVISDNN---YSWWIKLYFAII------FALVLFVAVNLAVGIYNKWDSTPVIIGISSKMTPI 59
            ::.|.|.:|   .::|..|:....      |||           ::.::.|.||.:.|:...
  Rat    98 IRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFAL-----------LFEEYLSYPVSLNINLNS--- 148

  Fly    60 DQIPFPTITVCNMNQAK----KSKVEHL------------------------------------- 83
            |::.||.:|||.:|..:    |.::|.|
  Rat   149 DKLVFPAVTVCTLNPYRYTEIKEELEELDRITEQTLFDLYKYNSSYTRQAGARRRSSRDLLGAFP 213

  Fly    84 ----------MPGSIRYAMLQKTCYKESN---------FSQYMDTQHRNETF------------- 116
                      .|.|.|.|....:..:::|         ....:..|::::.|
  Rat   214 HPLQRLRTPPPPYSGRTARSGSSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDAVRE 278

  Fly   117 ------SNFILDVS--------EKCADLIVSCIFHQQRIPCTDIFRETFVDEGLCCIFNVLHPYY 167
                  .|.:..:|        |...:.|.:|.|:|  .||.......|           .||.|
  Rat   279 WYRFHYINILSRLSDTSPALEEEALGNFIFTCRFNQ--APCNQANYSKF-----------HHPMY 330

  Fly   168 --LYKFKSPYIRDFTSSDRFADIAVDWDPISGYPQRLPSSYYPRPGVGVGTSMGLQIVLNGHVDD 230
              .|.|     .|..:|:.       |  :|..|               |.:.||.:.|....:|
  Rat   331 GNCYTF-----NDKNNSNL-------W--MSSMP---------------GVNNGLSLTLRTEQND 366

  Fly   231 YFCSSTNGQGFKILLYNPIDQPRMKESGLPVMIGHQTSFRIIARNVEATPS-------------- 281
            :....:...|.:::::...:...|.:.|..:..|.:||   |:...||..|
  Rat   367 FIPLLSTVTGARVMVHGQDEPAFMDDGGFNLRPGVETS---ISMRKEALDSLGGNYGDCTENGSD 428

  Fly   282 --IRNIHRTKRQCIFSDEQELLFYRYYTRRNCEAECDSMFFLRLCSCIPYYLPLIYP---NASVC 341
              ::|::.:|                ||::.|...|.....::.|.|.  |  :.||   ....|
  Rat   429 VPVKNLYPSK----------------YTQQVCIHSCFQENMIKKCGCA--Y--IFYPKPKGVEFC 473

  Fly   342 DVFHFECLNRAESQ----------IFDLQSSQCKEFCLTSCHDLIF--------FPDAFSTPFSQ 388
            |.       |.:|.          .|.|.|..|...|...|..:.:        :|...|..:..
  Rat   474 DY-------RKQSSWGYCYYKLQGAFSLDSLGCFSKCRKPCSVINYKLSAGYSRWPSVKSQDWIF 531

  Fly   389 KDVKAQTNYLTNFSSEYMRKNLAVVN-FFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIG--- 449
            :.:..|.||..|    ..|..:|.:| ||...||..:|...|.| ....:::.|...||..|
  Rat   532 EMLSLQNNYTIN----NKRNGVAKLNIFFKELNYKTNSESPSVT-MVSLLSNLGSQWSLWFGSSV 591

  Fly   450 FSVIFLAEIIYIILFVSTLLLILIF 474
            .||:.:||:|:.:|.::.|:|:..|
  Rat   592 LSVVEMAELIFDLLVITLLMLLRRF 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:459966	109/594 (18%)
Scnn1a	NP_113736.1	ENaC	80..677	CDD:273304	114/610 (19%)