DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk5 and ppk3

DIOPT Version :9

Sequence 1:	NP_996138.2	Gene:	ppk5 / 2768987	FlyBaseID:	FBgn0053289	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_726336.1	Gene:	ppk3 / 246504	FlyBaseID:	FBgn0050181	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	93/497 - (18%)
Similarity:	197/497 - (39%)	Gaps:	121/497 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 WWIKLYFAIIFALVLFVAVNLAVGIYNKWDSTPVIIGISSKMTPIDQIPFPTITVCNMNQAKKSK 79
            :|:.:..:.:.|.::...:.|     .::.|:|.:|.:.......:. ..|.:|:|..:.....|
  Fly    70 FWLAVVVSSVIAALVLSRLQL-----ERYFSSPTVISVDRDYRGWNG-SLPAVTLCYYDHIDSFK 128

  Fly    80 ----VEHLMPGSI-----------RYAMLQKTCYKESNFSQYMDTQHRNETFSNFILDVSEKCAD 129
                ::.:...||           .||::..|....:..:::.:.:..::.....::...::..:
  Fly   129 ANEYIQEMWNVSIIDEDYFYFMDFLYAVVNATAGNYAELAKFAEDERFDQIDLYEMIQRVDRPFE 193

  Fly   130 LIVSCI-----FHQQRIPCTDIFRETFVDEGLCCIFNVLHPYYLYKFKSPYIRDFTSSDRFADIA 189
            .::|..     .|.||:         ..:.|.|           |...||           ....
  Fly   194 QVISSFDAGFQVHVQRV---------MTERGAC-----------YAINSP-----------MSTV 227

  Fly   190 VDWDPISGY---PQRLPSSY-----YPRPGVGVGTSMGLQIVLNGHVDDYFCSSTNGQGFKILLY 246
            :...|:: |   ||.|...|     |.|..:...|.     ||:.| ..:..|:|..   .|:..
  Fly   228 LSGQPVA-YELMPQPLSCQYGKQQCYIRMDLYESTG-----VLDVH-SPFEVSATEA---NIVAL 282

  Fly   247 NPIDQPRMKESGLPVMIGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQELLFYRYYTRRNC 311
            :..|:             ...||:::  ...|:.::|.:...:|:|:|::| |....:.|::..|
  Fly   283 HKSDE-------------ITASFKVL--ETVASKNLRQLSVAQRKCVFNNE-ETSNLKIYSKSLC 331

  Fly   312 EAECDSMFFLRLCSCIPYYLPLIYPNASVCDVFHFECLNRAESQIFDLQSSQCKEFCLTSCHDLI 376
            .|.|.::..|.:|:|:|::.|  |.:...|:...||||...:..|:.|..  ||  |.::|.::
  Fly   332 LARCRAVMALEMCNCVPFFYP--YVDGPSCNPAGFECLLDFKWPIWALHI--CK--CPSTCTEI- 389

  Fly   377 FFPDAFSTPFSQKDVKAQTNYLTNFSSEYMRKNLAVVNFFHTDNY-----FRSSVRTSYTGPTEY 436
                    .::.:.||..:..:.|  :|.:..:....:.|..|..     .|..|..|:   .:.
  Fly   390 --------EYTMQTVKKSSWGVKN--NEEVASSETATSSFRWDLIPPKVRMRRDVVYSF---EDL 441

  Fly   437 MASTGGIMSLMIGFSVIFLAEIIYI-----ILFVSTLLLILI 473
            :.|.||:::|.:|.||:.|.|::::     :|.|.|||.:::
  Fly   442 VVSFGGVLALFVGVSVMGLVEMVHVLVNNLLLDVFTLLRLML 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:279230	88/477 (18%)
ppk3	NP_726336.1	ASC	59..464	CDD:279230	88/476 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920