Protein Alignment ppk5 and asic-2

DIOPT Version :10

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 534
• Identity: 115/534 - (21%)
• Similarity: 193/534 - (36%)
• Gaps: 151/534 - (28%)

  Fly     3 MLKYVISDNN---YSWWIKLYFAII--FALVLFVAVNLAVGIYNKWDSTPVIIGISSKMTPIDQI 62
            ::.:|.:.||   ..:||.::..::  ||..|::.:       .|:.|.|..  :::::....||
 Worm    21 VVPHVANANNKISRIFWIAIFLFVLGMFAYELYILI-------AKFFSYPAT--VNTEILFEKQI 76

  Fly    63 PFPTITVCNMNQAKKSKVE-HLMPGSIRYAMLQKTCYKES---NFSQ-----YMDTQHRNETF-- 116
             ||.:||||||..|.|.|: :....|:...|   |.|.::   .||.     |.|   .:||:
 Worm    77 -FPVVTVCNMNPYKYSVVKSNSAFSSVNTLM---TTYSDATVGTFSTDKWGLYAD---NDETYDL 134

  Fly   117 -----------SNFILDVSE-----KCADLIVSCIFHQQRIPCTDIFRETFVDE--GLCCIFNVL 163
                       :|.|.|.::     ..||||..|.|  ..|||::.....|:|.  |.|..||
 Worm   135 DSRAADALVLEANLISDTAKVPALYTYADLIQDCSF--AGIPCSESDFTKFIDPVYGACYSFN-- 195

  Fly   164 HPYYLYKFKSPYIRDFTSSDRFADIAVDWDPISGYPQRLPSSYYPRPGVGVGTSMGL---QIVLN 225
                                  .|.::::.             ..|.|:..|..:.|   |...|
 Worm   196 ----------------------EDASLNYS-------------VSREGIQFGLKLMLTVTQTKTN 225

  Fly   226 GHVDDYFCSSTNGQGFKILLYNPIDQPRMKESGLPVMIGHQTSFRI-IARNVEATPSIRNIHRTK 289
            |:.|.  ..:|...|.:|.:.:....|.:..:|:...:|::::..: :.:||.|       .:..
 Worm   226 GNTDS--LPTTKLAGARIGVNSRGSSPGLDSNGIDAGVGYESAVSVSLTQNVRA-------KKPY 281

  Fly   290 RQCIFSDEQELLFYR--YYTRRNCEAECDSMFFLRLCSCIPYYLPLIYPNASVCDVF--HFECLN 350
            ..|:..:.....:|:  .||...|...|.....:..|.|....|.| ....:.|...  ..:||.
 Worm   282 GTCVDREPDSSDYYKDFIYTLETCFNGCKQRDTIAKCQCANPRLAL-GSTDTACQPIKADLDCLQ 345

  Fly   351 RAESQIFDLQSSQ---------------CKEFCLTSCHDLIFFPDAFSTPF-----SQKDVKAQT 395
            ..:..    |:|.               |.|...|....|..||   ||.:     |...|.:.:
 Worm   346 TLKGN----QTSSTPNIDLLVECNCNPPCDESTYTPTVSLAQFP---STSYYVATSSTAGVGSCS 403

  Fly   396 NYLTNFSSE------YMRKNLAVVNFFHTDNYFRSSVRTSYTGPTEYMAST-----GGIMSLMIG 449
            :..:.|||:      |....:.:..|..|.:|      ..||....|..|.     ||...|.:|
 Worm   404 STNSKFSSKSDCQKWYNNNGMIIQVFLETLSY------ELYTETAGYTVSNVINDLGGQAGLWLG 462

  Fly   450 FSVIFLAEIIYIIL 463
            .|||.:.|:..::|
 Worm   463 LSVISVVEMTGLML 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:459966	114/528 (22%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	114/530 (22%)