Protein Alignment ppk5 and mec-4

DIOPT Version :10

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_510712.2
• Gene: mec-4 / 181728
• WormBaseID: WBGene00003168
• Length: 768
• Species: Caenorhabditis elegans
• Alignment Length: 654
• Identity: 108/654 - (16%)
• Similarity: 193/654 - (29%)
• Gaps: 232/654 - (35%)

  Fly    16 WIKLYFAIIFALVLFVAVNLAVGIYNKWDSTPVIIGISSKMTPIDQIPFPTITVCNMNQAKKS-- 78
            |:.|:...:..|.|     .|..:.:|::....|:.|..|   .|..|||.||:||:|..|.|
 Worm   111 WVVLFLGCMIMLYL-----NAQSVLDKYNRNEKIVDIQLK---FDTAPFPAITLCNLNPYKASLA 167

  Fly    79 ----------------------KVEH---------------------------------LMPGSI 88
                                  ..:|                                 ..||..
 Worm   168 TSVDLVKRTLSAFDGAMGKAGGNKDHEEEREVVTEPPTTPAPTTKPARRRGKRDLSGAFFEPGFA 232

  Fly    89 R-------------------YAMLQKTCYKESNFSQYMD-----TQHRNETFSNFILDVS----- 124
            |                   ..:|:.|..|..|.:...:     .::.||.:.|:.::.:
 Worm   233 RCLCGSQGSSEQEDKDEEKEEELLETTTKKVFNINDADEEWDGMEEYDNEHYENYDVEATTGMNM 297

  Fly   125 -EKCA------------DLIVSCIFHQ---QRIPC--------TDIFRETFVDEGLC-------- 157
             |:|.            |....|.|.:   ...||        |:.  :|..:...|
 Worm   298 MEECQSERTKFDEPTGFDDRCICAFDRSTHDAWPCFLNGTWETTEC--DTCNEHAFCTKDNKTAK 360

  Fly   158 -----CIFNVLHPYYLYKFKSP------YIRDFTSSD---------------------------- 183
                 ||.........|..|:|      |::..|.::
 Worm   361 GHRSPCICAPSRFCVAYNGKTPPIEIWTYLQGGTPTEDPNFLEAMGFQGMTDEVAIVTKAKENIM 425

  Fly   184 -----------------------------RFADIAVDW----DPISG--------YPQRLPSSYY 207
                                         :..||..|:    ||..|        ....|.|
 Worm   426 FAMATLSMQDRERLSTTKRELVHKCSFNGKACDIEADFLTHIDPAFGSCFTFNHNRTVNLTS--- 487

  Fly   208 PRPGVGVGTSMGLQIVLNGHVDDYFCSSTNGQGFKILLYNPIDQPRMKESGLPVMIGHQTSFRII 272
                :..|...||::::..:..||. .:|...|.::.:::..|.|.....|.....|:.:||.:.
 Worm   488 ----IRAGPMYGLRMLVYVNASDYM-PTTEATGVRLTIHDKEDFPFPDTFGYSAPTGYVSSFGLR 547

  Fly   273 ARNVEATPSIRNIHRTKRQCIFSDE-QELLFYRY-YTRRNCEAECDSMFFLRLCSCIPYYLPLIY 335
            .|.:...|:      ....|:...: .:.::..| |:...|...|.....|:.|.|.....| :.
 Worm   548 LRKMSRLPA------PYGDCVPDGKTSDYIYSNYEYSVEGCYRSCFQQLVLKECRCGDPRFP-VP 605

  Fly   336 PNASVCDV---FHFECLNRAESQIFDLQSS---QCKEFCLTSCHDLIFFPDAFSTPFSQKDVKAQ 394
            .||..||.   ...:||:...:.:..|..|   :|::.|..|.:.:.:.|..:.:...|..:.:.
 Worm   606 ENARHCDAADPIARKCLDARMNDLGGLHGSFRCRCQQPCRQSIYSVTYSPAKWPSLSLQIQLGSC 670

  Fly   395 TNYLTNFSSEYMRKNLAVVNFFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIGFSVIFLAEII 459
            .......:..| ::|.|:|..|:....|.....:...|....:|..||.:.|..|.|.:...|.:
 Worm   671 NGTAVECNKHY-KENGAMVEVFYEQLNFEMLTESEAYGFVNLLADFGGQLGLWCGISFLTCCEFV 734

  Fly   460 YIIL 463
            ::.|
 Worm   735 FLFL 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:459966	107/649 (16%)
mec-4	NP_510712.2	deg-1	86..736	CDD:273309	107/650 (16%)