Protein Alignment ppk5 and unc-8

DIOPT Version :9

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001294293.1
• Gene: unc-8 / 177494
• WormBaseID: WBGene00006748
• Length: 778
• Species: Caenorhabditis elegans
• Alignment Length: 651
• Identity: 116/651 - (17%)
• Similarity: 202/651 - (31%)
• Gaps: 228/651 - (35%)

  Fly     4 LKYVISDN---NYSWWIKLYFAIIFALVLFVAVNLAVGIYNKWDSTPVI--IGISSKMTPIDQIP 63
            :.||.:.:   .|.|           ..||:.:.:|..:...|..:..:  ..|.......:...
 Worm   117 IPYVATSSFFGRYVW-----------AALFMCMLMAFLLQTYWTMSEYLQYRTIIEMQLQFEAAA 170

  Fly    64 FPTITVCNMNQAKKSKV-----------------------EHLMPG-------SIRY-------- 90
            ||..||||:|..|.|::                       :.:.||       |:|.
 Worm   171 FPAATVCNLNAFKYSELTQYEEIKEGFDYWERVINARMMSDSMKPGGDILEAISVRKKRSKSRDQ 235

  Fly    91 -----------------AMLQKTCYKESNFSQYMDTQHRNETFSNFIL---DVS----------- 124
                             ..::.||   .|..|.:..::..|..::..:   ||:
 Worm   236 LLFPIDDEDLEGAVYQPVFVRCTC---MNMEQCVPNRNPLEVNASICMCFEDVTRGLIWPCYPTS 297

  Fly   125 ----EKCADLIVS--C------------IFHQQRIPCTDIFRETFVDEGLC------CIFNVLHP 165
                :||:...:|  |            ..|...:||            ||      |   ::||
 Worm   298 VWTVKKCSGCSISNTCPDPDGPNASKQIAKHNSPLPC------------LCQSISHHC---MVHP 347

  Fly   166 -----------YYLYKFKSPYIRDFTSSDR---FADI----AVDWDP-------ISGYPQ--RLP 203
                       |.:|....|...:.|.::.   .:|:    |:....       ::..|:  |..
 Worm   348 KDEIRWWNPNNYTVYSVTEPPTTEITETEEAFGLSDLKDAGAITTQTKENLIFLVAALPRETRRN 412

  Fly   204 SSY------------------------YPRPGVG-----------------VGTSMGLQIVLNGH 227
            .||                        :..|..|                 .|...||:::||.|
 Worm   413 LSYTLNEFVLRCSFNSKDCSMERDFKLHVDPEYGNCYTFNFNDSVELKNSRAGPMYGLRLLLNVH 477

  Fly   228 VDDYFCSSTNGQGFKILLYNPIDQPRMKESGLPVMIGHQTSFRIIARNVEATPSIRNIHRTKR-- 290
            ..||. .:|...|.:::::....:|.....|.....|..:||.:         ..:.:||...
 Worm   478 QSDYM-PTTEAAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGL---------KTKELHRLSAPW 532

  Fly   291 -QCIFSDEQELLFYRY---YTRRNCEAECDSMFFLRLCSCIPYYLPLIYPNASVCDV---FHFEC 348
             .|  ||....:.|.|   |:...|...|..:..|.:|.|.....||.......|:.   ...:|
 Worm   533 GNC--SDTFRPVPYIYNEHYSPEGCHRNCFQLKVLEICGCGDPRFPLPSEEHRHCNAKSKIDRQC 595

  Fly   349 LNR--AESQIFDLQSSQCKEFCLTSCHDLIFFPDAFSTPFSQKDVKAQTNYL--------TNFSS 403
            |:.  ::|..:.....||:  |...||:.:|.....::.:..::.|..|:..        |...:
 Worm   596 LSNLTSDSGGYHHLHEQCE--CRQPCHEKVFETAYSASAWPSQNFKIGTDCPAVSDIFNDTEACT 658

  Fly   404 EYMRKNLAVVNFFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIGFSVIFLAEIIYIILFVSTL 468
            ||.|:|.|.:..::....|.|...|:........:..||.:.|.||||||..||...:...:..|
 Worm   659 EYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWIGFSVITFAEFAELFCEICKL 723

  Fly   469 L 469
            :
 Worm   724 M 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:279230	115/640 (18%)
unc-8	NP_001294293.1	ASC	100..719	CDD:295594	115/644 (18%)
		deg-1	107..716	CDD:273309	115/641 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820