DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk5 and del-10

DIOPT Version :9

Sequence 1:	NP_996138.2	Gene:	ppk5 / 2768987	FlyBaseID:	FBgn0053289	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_495302.3	Gene:	del-10 / 174069	WormBaseID:	WBGene00020897	Length:	1069	Species:	Caenorhabditis elegans

Alignment Length:	409	Identity:	90/409 - (22%)
Similarity:	139/409 - (33%)	Gaps:	125/409 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LYFAIIFALVLFVAVNLAVGIYNK---WDSTPVIIGISSKMTPIDQIPFPTITVCNMNQAKKS-- 78
            |:..||.|.|:.|.|.    .|::   :.|.||...|.::..  .:|.|||:.:||.||.:.:
Worm    96 LWCMIIIAFVILVLVQ----CYSQIKLYISEPVATNIEAEYP--SKISFPTVAICNNNQFRLTYL 154

  Fly    79 ---KVEHLMPGSIRYAMLQKTCYKESNFSQYMDTQHRNE---TFSNFILDVSEKCADLIVSCIFH 137
               ::.:....||..::|......||.|    ||..|..   ....|:...:...:.:|:.|.:.
Worm   155 TGGRIMNRRSKSISGSLLSTGHDVESVF----DTVLRKSWDMDAVKFLRSAAHWKSRMILGCTWP 215

  Fly   138 QQRIPCTDIFRETFVDEGLCCIFNVLHPYYLYKFKSPYIRDFTSSDRFADIAVDWDPISGYPQRL 202
            .........|:..:...|||.                              |::.||
Worm   216 NGTSCKLSDFKAVWTTTGLCW------------------------------AINTDP-------- 242

  Fly   203 PSSYYPRPGVGVGTSMGLQIVLNGHVDDY---------FCSSTNGQGFKILLYNPIDQPRMKESG 258
               :.|....|.|...||:::||  |:.|         |.:.|. .|.|||:||..|.|....:|
Worm   243 ---HNPYEVTGSGEGHGLRLLLN--VESYERVDACTKHFRTKTL-PGLKILIYNQTDIPDSSMNG 301

  Fly   259 LPVMIGHQ-------------TSFRIIARN---VEATPSIRNIHRTKRQCIFSDEQELLFYRYYT 307
            :.|..|:.             |....|..|   :||:....|.... |.|...        ||.|
Worm   302 VNVPSGYSMDIPFKMQHRSKLTGVHCIEENDEQIEASTDFNNPENI-RTCTLR--------RYMT 357

  Fly   308 RRNCEAECDSMFFLRLCSCIPYYLPLIYPNAS------VCDV-FHFECLNRAESQIFDLQSSQ-- 363
                |.|       ..|.|.   |...|.:.|      .|:| .:|.|..:|..:|.:..::.
Worm   358 ----EVE-------NSCHCT---LRRAYTSNSTDVKMKACNVDQYFGCAQKAMQRIREEGTASTC 408

  Fly   364 ---CKEFCLTSCHDLIFFP 379
               ||....|:..|:...|
Worm   409 LPPCKSIDYTAWQDMNRLP 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:279230	90/409 (22%)
del-10	NP_495302.3	ASC	83..>419	CDD:279230	87/399 (22%)
del-10	NP_495302.3	ASC	<789..849	CDD:279230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820