Protein Alignment ppk5 and Asic3

DIOPT Version :10

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 486
• Identity: 91/486 - (18%)
• Similarity: 166/486 - (34%)
• Gaps: 167/486 - (34%)

  Fly    61 QIPFPTITVCNMNQAKKSKVEHLMPGSIRYAMLQKTCYKESNFSQYMDTQHRNETFSNFI----L 121
            |:.||.:|:||:|..::|:   |.|..:.:|.........:..:.|:....:......|:    .
Mouse    84 QLTFPAVTLCNINPLRRSR---LTPNDLHWAGTALLGLDPAEHAAYLRALGQPPAPPGFMPSPTF 145

  Fly   122 DVSEKCA-------DLIVSCIFHQQRIPC-TDIFRETFVDEGLCCIFNVLHPYYLYKFKSPYIRD 178
            |:::..|       |:::.|.:..|  || .:.|...|...|.|..||
Mouse   146 DMAQLYARAGHSLEDMLLDCRYRGQ--PCGPENFTVIFTRMGQCYTFN----------------- 191

  Fly   179 FTSSDRFADIAVDWDPISGYPQRLPSSYYPRPGVGVGTSMGLQIVLNGHVDDYF-----CSSTNG 238
              |..:.|::...                |:.|.|    .||:|:|:...::|.     ...|..
Mouse   192 --SGAQGAELLTT----------------PKGGAG----NGLEIMLDVQQEEYLPIWKDMEETPF 234

  Fly   239 Q-GFKILLYNPIDQPRMKESGLPVMIGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQELLF 302
            : |.::.::...:.|.:.:.|.....||||                        .:...:|:|.|
Mouse   235 EVGIRVQIHGQEEPPAIDQLGFGAAPGHQT------------------------FVSCQQQQLSF 275

  Fly   303 Y------------------------------RYYTRRNCEAECDSMFFLRLCSCIPYYLPLIYPN 337
            .                              ..|:...|...|:|.:..|.|.|...::|   .|
Mouse   276 LPPPWGDCNTASVDPDFDPEPSDPLGSPSSSPPYSLIGCRLACESRYVARKCGCRMMHMP---GN 337

  Fly   338 ASVCDVFHF-ECLNRA--ESQIFDL-------------------------QSSQCKEFCLTSCHD 374
            :.||....: :|.:.|  ::.:|.|                         .:...|:.|:  |
Mouse   338 SPVCSPQQYKDCASPALGKAHLFSLPVPIHSDIDHNPLGQVLLFLALRPADAMLRKDTCV--C-- 398

  Fly   375 LIFFPDAFSTPFSQKDV-------KAQTNYLT---NFSSEYMRKNLAVVN-FFHTDNYFRSSVRT 428
                |:..:|....|::       :|...||.   |.|..|:.:|:.|:: ||...||.....:.
Mouse   399 ----PNPCATTRYAKELSMVRIPSRASARYLARKYNRSETYITENVLVLDIFFEALNYEAVEQKA 459

  Fly   429 SYTGPTEYMASTGGIMSLMIGFSVIFLAEII 459
            :|. .:|.:...||.|.|.||.|::.:.||:
Mouse   460 AYE-VSELLGDIGGQMGLFIGASLLTILEIL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:459966	91/486 (19%)
Asic3	XP_006535700.1	ENaC	21..546	CDD:273304	91/486 (19%)