Protein Alignment ppk5 and Asic1

DIOPT Version :10

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001276720.1
• Gene: Asic1 / 11419
• MGIID: 1194915
• Length: 559
• Species: Mus musculus
• Alignment Length: 494
• Identity: 100/494 - (20%)
• Similarity: 171/494 - (34%)
• Gaps: 160/494 - (32%)

  Fly    22 AIIFALVLFVA-VNLAVGIYNKWDSTPVIIGISSKMTPIDQIPFPTITVCNMNQAKKSKVEHLMP 85
            |.:.||..|:. |...|..|..:....::..:::     .::.||.:|.||.|..:.|::.:  |
Mouse    94 AFVIALGAFLCQVGDRVAYYLSYPHVTLLDEVAT-----TELVFPAVTFCNTNAVRLSQLSY--P 151

  Fly    86 GSIRYA-MLQKTCYKESN-------------FSQYMDTQHRNETFSNFILDVSEKCADLIVSCIF 136
            ..:..| ||.   ..||:             ||......||      |......:..|:::.|.:
Mouse   152 DLLYLAPMLG---LDESDDPGVPLAPPGPEAFSGEPFNLHR------FYNRSCHRLEDMLLYCSY 207

  Fly   137 HQQRIPC-TDIFRETFVDEGLCCIFNVLHPYYLYKFKSPYIRDFTSSDRFADIAVDWDPISGYPQ 200
            ...  || ...|...|...|.|..||                                  ||...
Mouse   208 CGG--PCGPHNFSVVFTRYGKCYTFN----------------------------------SGQDG 236

  Fly   201 RLPSSYYPR-PGVGVGTSMGLQIVLNGHVDDYF-----CSSTNGQ-GFKILLYNPIDQPRMKESG 258
            |      || ..:..||..||:|:|:...|:|.     ...|:.: |.|:.:::..:.|.:.:.|
Mouse   237 R------PRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQLG 295

  Fly   259 LPVMIGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQELL-----------------FYRYY 306
            ..|..|.||                        .:...||.|:                 |:..|
Mouse   296 FGVAPGFQT------------------------FVSCQEQRLIYLPSPWGTCNAVTMDSDFFDSY 336

  Fly   307 TRRNCEAECDSMFFLRLCSCIPYYLPLIYPNASVCDVFHF-ECLNRAESQIFDLQSSQCKEFCLT 370
            :...|..:|::.:.:..|:|...::|   .:|..|....: ||.:.|    .|....:.:|:|:.
Mouse   337 SITACRIDCETRYLVENCNCRMVHMP---GDAPYCTPEQYKECADPA----LDFLVEKDQEYCVC 394

  Fly   371 S--CH--------DLIFFPDAFSTPFSQKDVKAQTNYLT---NFSSEYMRKNLAVVN-FFHTDNY 421
            .  |:        .::..|.           ||...||.   |.|.:|:.:|:.|:: ||...||
Mouse   395 EMPCNLTRYGKELSMVKIPS-----------KASAKYLAKKFNKSEQYIGENILVLDIFFEVLNY 448

  Fly   422 FRSSVRTSY--TGPTEYMASTGGIMSLMIGFSVIFLAEI 458
            .....:.:|  .|   .:...||.|.|.||.|::.:.|:
Mouse   449 ETIEQKKAYEIAG---LLGDIGGQMGLFIGASILTVLEL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:459966	100/494 (20%)
Asic1	NP_001276720.1	ENaC	63..541	CDD:273304	100/494 (20%)