Protein Alignment ppk5 and Asic2

DIOPT Version :10

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_006532059.1
• Gene: Asic2 / 11418
• MGIID: 1100867
• Length: 596
• Species: Mus musculus
• Alignment Length: 503
• Identity: 108/503 - (21%)
• Similarity: 192/503 - (38%)
• Gaps: 113/503 - (22%)

  Fly    36 AVGIYNKWDSTPVIIGIS-SKMTPID-----QIPFPTITVCNMNQAKKSKVEHLMPGSIRYA--- 91
            ::|:...|.|..::..:| ...|.:.     |:|||.:||||.|..   :...|..|.:.||
Mouse    96 SLGLLLSWSSNRLLYWLSFPSHTRVHREWSRQLPFPAVTVCNNNPL---RFPRLSKGDLYYAGHW 157

  Fly    92 ----MLQKTC------------------YKESNFSQYMDTQHRNETFSNFILDVSEKCADLIVSC 134
                :..:|.                  .|.::|..::..:|.....:.|:..:..:..|:::||
Mouse   158 LGLLLPNRTARPLVSELLRGDEPRRQWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSC 222

  Fly   135 IFHQQRIPCTDIFRETFVDEGLCCIFNVLHPYYLYKFKSPYIRDFTSSD----RFADIAVDWDPI 195
            .:..:                ||      .|:.......| .|:...||    |..: |:.|.|.
Mouse   223 KYRGE----------------LC------GPHNFSSVSCP-PREPALSDPALPRSPE-ALRWAPG 263

  Fly   196 SGYPQRLPSSYYP----------RP---GVGVGTSMGLQIVLNGHVDDYFC------SSTNGQGF 241
            :|:...:.:.|..          :|   .|..||..||:|:|:...|:|..      .:|...|.
Mouse   264 TGHQAPVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGV 328

  Fly   242 KILLYNPIDQPRMKESGLPVMIGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQELLFYRYY 306
            |:.:::..:.|.::|.|..|..|.||......:.:...|......|       |.|..|.|:..|
Mouse   329 KVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECR-------SSEMGLDFFPVY 386

  Fly   307 TRRNCEAECDSMFFLRLCSCIPYYLPLIYPNASVC-DVFHFECLNRAESQIFDLQSSQCKEFCLT 370
            :...|..:|::.:.:..|:|...::|   .:|..| ...|.||...|...:.:..|:.|  .|.|
Mouse   387 SITACRIDCETRYIVENCNCRMVHMP---GDAPFCTPEQHKECAEPALGLLAEKDSNYC--LCRT 446

  Fly   371 SCH--------DLIFFPDAFSTPFSQKDVKAQTNYLTNFSSEYMRKNLAVVN-FFHTDNYFRSSV 426
            .|:        .::..|...|..:.:|..        |.|.:|:.:|:.|:: ||...||.....
Mouse   447 PCNLTRYNKELSMVKIPSKTSAKYLEKKF--------NKSEKYISENILVLDIFFEALNYETIEQ 503

  Fly   427 RTSYTGPTEYMASTGGIMSLMIGFSVIFLAEII-YIILFVSTLLLILI 473
            :.:|. ....:...||.|.|.||.|::.:.|:. ||...:...||.|:
Mouse   504 KKAYE-VAALLGDIGGQMGLFIGASILTILELFDYIYELIKEKLLDLL 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:459966	103/488 (21%)
Asic2	XP_006532059.1	ENaC	64..590	CDD:273304	108/503 (21%)