Protein Alignment ppk5 and asic2

DIOPT Version :10

• Sequence 1: NP_996138.2
• Gene: ppk5 / 2768987
• FlyBaseID: FBgn0053289
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_004918663.1
• Gene: asic2 / 100492214
• XenbaseID: XB-GENE-6033380
• Length: 541
• Species: Xenopus tropicalis
• Alignment Length: 528
• Identity: 106/528 - (20%)
• Similarity: 186/528 - (35%)
• Gaps: 143/528 - (27%)

  Fly     4 LKYVISD----NNYSWWIKLYFAIIFALVLFVAVNLAVGIYNKWDSTPVIIGIS----------- 53
            |||:.|.    .:.::|             |:|...::|.:..|.|..::..:|
 Frog    53 LKYICSPKLAFRHRTFW-------------FLAFFTSLGFFLSWSSNRLLYWLSFPSHTRVQLEW 104

  Fly    54 SKMTPIDQIPFPTITVCN-------------------------MNQAKKSKVEHLMPGSIRYAML 93
            ||     ::.||.:|.||                         .|:..:..:..|:|...|
 Frog   105 SK-----ELAFPAVTFCNNNPVRFHRLSKSDLYFAGYWLGLLFANRTARPMLAELLPEDRR---- 160

  Fly    94 QKTCYKESNFSQYMDTQHRNETFSNFILDVSEKCADLIVSCIFHQQRIPC-TDIFRETFVDEGLC 157
             |...|.::|..::..::.:.....|:..:..:..|:::||.:..:  .| ...|...|...|.|
 Frog   161 -KWFQKLADFRLFLPPRNFDGISVGFMDRLGHQLEDMLLSCKYRGE--ACGPHNFSTVFTRYGKC 222

  Fly   158 CIFNVLHPYYLYKFKSPYIRDFTSSDRFADIAVDWDPISGYPQRLPSSYYPRPGVGVGTSMGLQI 222
            .:||                                  ||...| |.....:.|.|    .||:|
 Frog   223 YMFN----------------------------------SGQDGR-PVLTTVKGGAG----NGLEI 248

  Fly   223 VLNGHVDDYFC------SSTNGQGFKILLYNPIDQPRMKESGLPVMIGHQTSFRIIARNVEATPS 281
            :|:...|:|..      .:|...|.|:.:::..:.|.::|.|..|..|.||......:.:...||
 Frog   249 MLDIQQDEYLPIWGDTEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPS 313

  Fly   282 IRNIHRTKRQCIFSDEQELLFYRYYTRRNCEAECDSMFFLRLCSCIPYYLPLIYPNASVCDVFHF 346
                  ....|.|| |....|:..|:...|..:|::.:.:..|.|...::|   .:|..|....:
 Frog   314 ------PWGACRFS-ELGSDFFPVYSISACRIDCETRYIVENCGCKMVHMP---GDAPFCTPEQY 368

  Fly   347 -ECLNRAESQIFDLQSSQCKEFCLTSCH--------DLIFFPDAFSTPFSQKDVKAQTNYLTNFS 402
             ||...|...:.:.....|  .|...|:        .::..|...|..:.:|..        |.|
 Frog   369 KECAEPALDLLAEKDGGNC--VCTIPCNVTRYNKELSMVKIPSKTSAKYLEKKF--------NKS 423

  Fly   403 SEYMRKNLAVVN-FFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIGFSVIFLAEII-YIILFV 465
            .:|:..|:.|:: ||...||.....|.:|. ....:...||.|.|.||.|::.:.|:. ||...:
 Frog   424 EKYILDNILVLDVFFEALNYETIEQRKAYE-VAGLLGDIGGQMGLFIGASILTILELFDYIYELI 487

  Fly   466 STLLLILI 473
            ...||.|:
 Frog   488 KEKLLDLL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk5	NP_996138.2	ASC	4..460	CDD:459966	101/513 (20%)
asic2	XP_004918663.1	ENaC	49..497	CDD:273304	106/528 (20%)