Protein Alignment CG33287 and CG12983

DIOPT Version :10

• Sequence 1: NP_001137993.1
• Gene: CG33287 / 2768986
• FlyBaseID: FBgn0053287
• Length: 1101
• Species: Drosophila melanogaster
• Sequence 2: NP_001137992.1
• Gene: CG12983 / 40319
• FlyBaseID: FBgn0037040
• Length: 1104
• Species: Drosophila melanogaster
• Alignment Length: 1144
• Identity: 415/1144 - (36%)
• Similarity: 640/1144 - (55%)
• Gaps: 113/1144 - (9%)

  Fly    14 LISEAEMMERQKNYTTRMHDIAAACATFRKSLLQFRLLEEERTNQGRWDQYLRCDGLPKVRSPIE 78
            |:||.|.|.|:..|..|:.|:..:.|....::.:::.|::::....:|:.||.|||||....|.|
  Fly    18 LLSEEEWMARRNIYMQRLADLKTSVAFIDDAVEEYKELQKQKLRNDKWNSYLACDGLPNPSRPAE 82

  Fly    79 IRTFLAKIRHFEEIETKNSIDWTMGVDERSVLSQNIYQKDLTRPVLQRTAVDNPGSYFESNLKKC 143
            ||.|:.::...|:....|.|.|.:.|||.|||||...:.|.||.:::::. .|.|..::..:::.
  Fly    83 IRKFIFQLNFMEQESCANEISWVLSVDECSVLSQAPDRCDRTRKIMEKSR-PNVGQLYDETVQRI 146

  Fly   144 MDVLQQVDILMDNEVEMERMNKSVLVDLLEVYRDVQLEIESLFDRLTYRILRMQKAYMESVNGIV 208
            :..:::|..::.|:.|:..:....:.:|.::..::..||||.||:||||::....|.|.:.:.|:
  Fly   147 LATIERVQRVLRNDDELVHLPTFQVRELDKIPNELYGEIESFFDKLTYRVVSSPDALMMNKDSIL 211

  Fly   209 ARWSHSCDLWRMDLWGLYNVPIIFQQLEVPLMIVDFKETSVKVQVPLSVLCDCITIRCVHTDFDH 273
            :.:.:.|..:.:::|||.:|||.|..|::|:|..|.....|.:|:|||||||.:|:|||.|.||.
  Fly   212 SCYCYKCSNFDLEIWGLQDVPIRFNYLKLPVMCSDLNCVGVTIQLPLSVLCDNLTLRCVRTFFDP 276

  Fly   274 HSPHAKSYEPLTVESIFMPNAGLTDMEESVVGEWLMQNDIQEETLNNMNRRREEYDELMQLIAER 338
            .|..|||:| |.::|..:||.||.|:.:||:.||:.|.||||:.:..|......|:|.:..||
  Fly   277 LSHLAKSFE-LVIDSSVIPNCGLVDIADSVMSEWMTQMDIQEDLVVKMETEMRAYNEAIAFIA-- 338

  Fly   339 TEQAAKEAKFGKGGDGDKRPKIVIPKTPKTVPLVPQGMYPDVFKEFLFREEDQYKKFLSTYFHPD 403
             :..|||.:      ..::.||.|||.||....:|.||:||..|.||..|:.....|.:.||||.
  Fly   339 -QAEAKEKR------KSQKKKIAIPKPPKMPQELPAGMFPDPRKIFLEHEKRDCTDFFNRYFHPG 396

  Fly   404 NLSLTPEEVNLRECIIVGGIYNISFVRRPDQTQFEKFNIVLHEDGRVLKVIPQVVAKQDNRKSRL 468
            |::|.|.|||||..||:|||.::.||.:.....:|||||.||||||||:....::.:....:..:
  Fly   397 NINLLPSEVNLRRFIILGGIVSLVFVGKAKHASYEKFNITLHEDGRVLRKSLNILDESSTEECSM 461

  Fly   469 TEYTRMTLGTSQMK-------------LSEEELPFFVVTVQLPPHLCRWGKPEVCHYLR-EL-QT 518
             :.:::.:||..|:             |..:|||::.:|.::|.|||.||:|.||.:.. |: :|
  Fly   462 -QPSKLDIGTDIMRDTEVGEASKIPLHLEPDELPYYFLTFKVPNHLCLWGEPIVCQFFESEIEET 525

  Fly   519 PTRA--------------PDRSTLVTLN--VLSPIRISSELSKREDGSVQS-----------TLA 556
            |::|              |.|.:....|  ||.....|..:|..|:...||           ...
  Fly   526 PSKAKAEELDKKLDKKKKPVRKSSRKENESVLRVPTTSGSVSMSEEKPPQSNRPTYHQPARENSV 590

  Fly   557 NQFSPPLKSLLKQS----------ITYGHFPLRGEPIANFNLDKSLNKIEIMKLEKMCLPRIISS 611
            |.:.|...::::||          .|:.:..|..|||:..||  ||       |:..||||||||
  Fly   591 NIYRPSALTIVRQSGMETEQIQYKKTFKNSNLVKEPISKRNL--SL-------LQDQCLPRIISS 646

  Fly   612 FKFPSEFVEDQLTSEALKSRP-NRLVKRLDTETAVEAKTPAEIY-FEYESQERPERAFPIFEKTV 674
            .:||.:|.:|::.::|:|..| .:|.||..||:.  ..|..|.: |.||.|..|||.:|.|..|.
  Fly   647 LRFPRDFQDDKMEAQAMKKIPVTQLYKRQLTESV--GSTQIEKFSFNYEDQSNPERLYPKFPVTE 709

  Fly   675 AIEFSSAAELMPSIECGNKATACGLLSTLEDIKEKYLQRPQELLDQI--QVQVSKKSEKKAEKWE 737
            .:.    .|...:.....:.|..|||.|||.||:|||..|:.:::|.  .|::|:|:      :.
  Fly   710 DLR----VETDRTDSSKEEGTMLGLLRTLEGIKDKYLDAPKRIVEQTTHAVRMSRKA------YS 764

  Fly   738 NKNADGRSSAFSFRDRSSFANVNGKKTALDAKTKINETEIMITISTSENKMEIPSTSKTRTRRSG 802
            :.....||...|:..|.|...::....::.....| |.|:..|..|.|..::    |:..:|...
  Fly   765 DPIPTTRSRRQSYFGRRSVRQLDSSIMSIARPVDI-EYELSETSDTGEQMIK----SRKDSRLPS 824

  Fly   803 SVMKRRSTRKSARMEDMDRFRPMDSEPPVLLDHWTKEYIMESQINLETNTLTFRTDRLGIFGLAF 867
            :::.:.:..::|.                   |||.|:|:||..|.|:..:..:|||||.||.|:
  Fly   825 TILSQSAEPRNAA-------------------HWTTEFILESSFNKESKVVIVKTDRLGHFGFAY 870

  Fly   868 KRYEHFPFRDWCLQPSEDNPDEVILSLDTFHVRMFFYISARGVRGYVTDLVKGYTAKPVKYLEIV 932
            :||.|||||.|.|:.:|.|.||:||:|||:|||:.|:||..|:|.:..|:.|.|..:|.||::|.
  Fly   871 RRYAHFPFRHWELEKNEQNHDEIILTLDTYHVRVVFFISKDGIRCHAIDIPKEYVHRPFKYIDID 935

  Fly   933 EPISDFRELRKLLIERNLNIFAENDASYYITNGYFSIKHIALELHTYNTMALQCKLMKFCRSSWN 997
            :|||||.||||.|.:.|||:|||.||.:||..||||.||:|.|||.|:.:|:..|||||.||.||
  Fly   936 KPISDFVELRKRLQDMNLNVFAELDACFYIDQGYFSQKHLAAELHIYDAIAVHGKLMKFSRSQWN 1000

  Fly   998 RLAQRRDIIVEMKIAKDNSDYSEVTMRITPEKTTFVKISEMCSDDVNVVKLRYEDTWRNVNNYND 1062
            |||:.||:::.::..:|..|.||||:|:|||.:|||.:||:||||..|:||.|:.||||:..|:|
  Fly  1001 RLAKDRDLVLCLQNTRDIHDGSEVTVRVTPEVSTFVDVSELCSDDTKVIKLNYKSTWRNMGTYSD 1065

  Fly  1063 FGQAIYSLNPHTLEGSNKDAMLFVYLKRLLNEIRPLSYS 1101
            ..|.|.|:.|...:..|:||....|:::||.||||||:|
  Fly  1066 LHQLINSMYPQATDMRNRDANQMYYIRQLLQEIRPLSFS 1104

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33287	NP_001137993.1	Casc1_C	835..1053	CDD:432508	119/217 (55%)
CG12983	NP_001137992.1	Casc1_N	17..152	CDD:464947	41/134 (31%)
		Casc1_C	838..1056	CDD:432508	119/217 (55%)