Protein Alignment CG33287 and CG15373

DIOPT Version :10

• Sequence 1: NP_001137993.1
• Gene: CG33287 / 2768986
• FlyBaseID: FBgn0053287
• Length: 1101
• Species: Drosophila melanogaster
• Sequence 2: NP_001097013.2
• Gene: CG15373 / 32784
• FlyBaseID: FBgn0030889
• Length: 1162
• Species: Drosophila melanogaster
• Alignment Length: 1220
• Identity: 268/1220 - (21%)
• Similarity: 475/1220 - (38%)
• Gaps: 317/1220 - (25%)

  Fly    51 LEEERTNQGRWDQYLRCDGLPKVRSPIEIR-------TFLAKIRHFEEIETKNSIDWTMGVDERS 108
            :::...::..|::::||:|||...||.::|       |.:|| ||.|      |.:|.:..|||:
  Fly    87 IKDGERHERDWEKFMRCNGLPNAASPSDLRKYIHQWHTDIAK-RHLE------SRNWLLRTDERT 144

  Fly   109 VLSQNIYQKDLTRPVLQRTAVDNPGSYFESNLKKCMDVLQQVDILMDNEVEMERMNKSVLV--DL 171
            :|:|:....|||| :..|......|..:...:|:.:.:|.::|.::..:      .||.|:  ||
  Fly   145 LLTQDAQVPDLTR-ISLRQQQGRLGDVYAHRIKEVLGILNELDEMLPFK------QKSALIAADL 202

  Fly   172 LEVYRDVQLEIESLFDRLTYRILRMQKAYMESVNGIVARWSHSCDLWRMDLWGLYNVPIIFQQLE 236
            :::..::::.::...|..||:.:...:..||.....|::..:|.|:::..:|      ...:..:
  Fly   203 VKLKTEMRVFLKQHLDEFTYKTMSHIERDMEIDRPGVSKHIYSSDVFQSFVW------TFSKDAQ 261

  Fly   237 VPL------------MIVDFKETSVKVQVPLSVLCDCITIRCVHTDFDHHSPHAKSYEPLTVESI 289
            :.|            ..:||....:::.:|.:|......:|.:..::||.|.:..||   .::..
  Fly   262 ISLNPKARIGEQSSHNEIDFPTIEMQISLPPTVHLQSSALRGLWLNYDHFSDYCSSY---CLKHA 323

  Fly   290 FMPNAGLTDMEESVVGEWLMQNDIQEETLNNMNRR--REEYDELMQLIAERTEQAAKEAKFGKGG 352
            ...||.:....:.   ||..:.:|.:..|::..|.  ..|.::|.|.....:.|..:|..:
  Fly   324 RSANANILRQTKR---EWRKRKEILQAMLDDCGREIPLSELEQLTQDQHSASSQPPRERTY---- 381

  Fly   353 DGDKRPKIVIPKTPKTVPLVPQGMYPDVFKEFLFREEDQYKKFLSTYFHPDNLSLTPEEVNLREC 417
            |.||                       ::.|:    ||:..|.......|:...:...:||||:.
  Fly   382 DVDK-----------------------LYAEY----EDELSKAHRRAIGPEAYGMLETDVNLRKY 419

  Fly   418 IIVGGIYNISFVRRPDQTQ----------FEKFNIVLHED-GRVLK----VIPQVVAKQDNRKSR 467
            .|:||:|.|.|:..|.|.:          ....|.::|:: .:..|    |:|.|        .|
  Fly   420 RIIGGVYCIDFLETPQQDKQLNARSFIRTITSANSLVHKEYYQTYKPPPPVLPGV--------RR 476

  Fly   468 LTEYTRMTLGTSQMKLSEEEL-PFFVVTVQL--------PPHLCRWG--------------KPEV 509
            |.|...     ::|::.|..| ...:||:||        ||..|||.              ||||
  Fly   477 LPEEIE-----AEMRMIEAALDKLALVTLQLPDSVIWFEPPVACRWETNVETLEMELADGMKPEV 536

  Fly   510 CHYLRE------------------LQTPTRAPDRSTLVTLNVLS-----PIRISSELSKREDGSV 551
            .....|                  ..|||.|...||....:.|.     |.|:.|:.|.....|.
  Fly   537 QKPHGEGDGEADGTGAVSGTAAATTATPTEATPLSTHAQPSPLKSSPRCPARMRSQKSDIGGESR 601

  Fly   552 QSTL--ANQFSPPLKSLLKQSITYG------------HFPLRGE---PIANFNLDKSLNKIEIMK 599
            |..|  .|.|.  |:::......||            .|.:|.|   |:    :...|.:.::|.
  Fly   602 QQVLREINDFD--LRAIPSDVDLYGLVKDFVVPRLPQGFCVRLEQSTPV----MSTGLRQRKVMF 660

  Fly   600 LEKMCLPRIISSFKFPSEFVEDQLTSE------ALKSRPNRLVKRLDTETAVEAKTPAEIYFEYE 658
            |.:....|:...    .:..:|||...      .|.|:|....:.||||      .|||:
  Fly   661 LARQAHIRLGQG----KDMADDQLEIPKELQRLQLNSKPGLGAEFLDTE------EPAEM----- 710

  Fly   659 SQERPERAFP--IFEKTVAIEFSSAAELMPSIECGNKATACGLLSTLEDIKEKY--LQRP----Q 715
                    ||  .|:|.:.....:.....|:...|.      |.|.|.|..::.  ||.|    :
  Fly   711 --------FPPLCFDKLLKFRQMAPRSRGPAHLQGY------LFSQLIDDMDRLWRLQLPRDQQE 761

  Fly   716 ELLDQIQVQV-------SKKSEKKAEKWENKNADG---------------------RSSAFSF-- 750
            |::.||..|:       |:..||:..:.||   ||                     .::||::
  Fly   762 EIIQQISEQLSPTGSRTSEPGEKEPRETEN---DGDLAENMQPLSQELVDVLQPATAAAAFAYYT 823

  Fly   751 -----RD---------RSSFANVNGKKTALDAKTKINE-TEIMITISTSENKMEIPSTSKTRTRR 800
                 ||         .||....|...::.|....::. .|::...||:.|.:.......|.:..
  Fly   824 GISFVRDSQLPAEPEPESSAKRSNSMDSSEDDDDDVDSLVELLEGASTAANTLHDLLGPATNSDN 888

  Fly   801 SGSVMKRRSTRKSARMEDMDRFRPMDSEPPVLLDHWTKEYIMESQINLETNTLTFRTDRLGIFGL 865
            |.|..|::.:..:|                :....|:...:.:::.|.:..::.|||.||||||.
  Fly   889 SDSESKQKMSNVAA----------------ITQGKWSTRDVHDTKFNEDKLSIQFRTGRLGIFGF 937

  Fly   866 AFKRYEHFPFRDWCLQPSEDNPDEVILSLDTFHVRMFFYISARGVRGYVTDLVKGYTAKPVKYLE 930
            |..:|.:.|::.|.|:|...||..:|.|.....:.:...|:.   .||..:..:|.:.:.:  .:
  Fly   938 ALNKYSNMPYQTWDLRPDMKNPGTIIFSFTASLISLDMTITK---SGYTVNNFQGGSTQGI--TD 997

  Fly   931 IVEPISDFRELRKLLIERNLNIFAENDASYYITNGYFSIKHIALELHTYNTMALQCKLMKFCRSS 995
            ::.......||:..||...::||.:.||..| |.|... |:..:|:|.|..::...:...|..|.
  Fly   998 MIGKTLSLSELKATLILSAVDIFPDEDAFCY-TEGSCE-KNYVMEMHCYACLSTLAQSHNFSWSR 1060

  Fly   996 WNRLAQRRDIIV---EMKIAKDNSDYSEVTMRITPEKTTFVKISEMCS--DDVNVVKLRYEDTWR 1055
            ||.||..|..::   |:...|....||  |:.:||.||:.:..:|:.:  :.|.:..:.|
  Fly  1061 WNLLAGSRTAVLLVRELIEGKKVPYYS--TLLVTPLKTSIIDCTEVSASFNAVGIPGMEY----- 1118

  Fly  1056 NVNNYNDFGQAIYSLN-PHTLEGS-----NKDAMLFVYLKRLLNEIRPLS 1099
                |.|    :|.|: .|...||     ..:.:|...:.::|..|||||
  Fly  1119 ----YAD----LYQLSQAHAQPGSLEKQRTMNPVLRDNVAKILMAIRPLS 1160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33287	NP_001137993.1	Casc1_C	835..1053	CDD:432508	59/222 (27%)
CG15373	NP_001097013.2	Casc1_N	14..>126	CDD:464947	10/38 (26%)
		Casc1_C	908..1104	CDD:432508	56/204 (27%)