Protein Alignment CG33287 and Dnai7

DIOPT Version :10

• Sequence 1: NP_001137993.1
• Gene: CG33287 / 2768986
• FlyBaseID: FBgn0053287
• Length: 1101
• Species: Drosophila melanogaster
• Sequence 2: NP_796196.3
• Gene: Dnai7 / 320662
• MGIID: 2444480
• Length: 730
• Species: Mus musculus
• Alignment Length: 1145
• Identity: 186/1145 - (16%)
• Similarity: 326/1145 - (28%)
• Gaps: 524/1145 - (45%)

  Fly    17 EAEMMERQKNYTTRMHDIAAACATFRKS--LLQFRLLE---EERTNQGR-------WDQYLRCDG 69
            |.:.:||:|.......|:.      |:|  |.:..|||   .|...|.|       |..|..|||
Mouse    50 EIQRIEREKWSLLEKKDLE------RRSQELEELALLEGCFPEAEKQKREIRALAQWKHYTECDG 108

  Fly    70 LPKVRSPIEIRTFLA-----KIRHFEEIETKNSIDWTMGVDERSVLSQN-IYQKDLTRPVLQRTA 128
            .|......|:.||::     |.:.||::..|:.:..::....:.:|.:. .|:.|      .||.
Mouse   109 SPDPWVAQEMNTFISLWEEEKNQAFEQVMEKSKLVLSLIEKVKLILLETPTYELD------HRTV 167

  Fly   129 VDNPGSYFESNLKKCMDVLQQVDILMDNEVEMERMNKSVLVDLLEVYRDVQLEIESLFDRLTYRI 193
            :.:.||...                              |.:||.:..:|..|:          :
Mouse   168 LQHQGSILR------------------------------LQELLSLKINVATEL----------L 192

  Fly   194 LRMQKAYMESVNGIVARWSHSCDLWRMDLWGLYNVPIIFQQLEVPLMI------------VDFKE 246
            ||......:...|                    |:..|.:...|.|.:            |.|.|
Mouse   193 LRQASNLADLDTG--------------------NMEKIIKDENVTLYVWANLKKNPRHRSVRFSE 237

  Fly   247 TSVKVQVPLSVLCDCITIRCVHTDFDHHSPHAKSYEPLTVESIFMPNAGLTDMEESVVGEWLMQN 311
            |.:..::|..:....:.:|.:||.:||.:|    ..|:.|            .|::       ||
Mouse   238 TQIGFEIPRILATSNVALRLLHTRYDHITP----LFPIAV------------TEQN-------QN 279

  Fly   312 DIQEETLNNMNRRREEYDELMQLIAERTEQAAKEAKF---GKGGDGDKRPKIVIPKTPKTVPLVP 373
            .:..|.:|               :.|.||:|..|.|.   .|..:.|::||   .:..:.:.||
Mouse   280 PVGAEQVN---------------VEESTEKAMTEEKLFTEEKAANEDEQPK---AEQERELNLV- 325

  Fly   374 QGMYPDVFKEFLFREEDQYKKFLSTYFHPDNLSLTPEEVNLRECIIVGGIYNISFVRRPDQTQFE 438
                         :||::|:...:|
Mouse   326 -------------QEENKYEAIENT---------------------------------------- 337

  Fly   439 KFNIVLHEDGRVLKVIPQVVAKQDNRKSRLTEYTRMTLGTSQMKLSEEELPFFVVTVQL------ 497
                              |:.:..:.:...::.|::.|   :|||..|.    |:..||
Mouse   338 ------------------VLQRTSDSEGEDSQTTQLEL---EMKLLSEA----VLAAQLCLVENV 377

  Fly   498 --PPHLCRWGKPEVCHYLRELQTPTRAPDRSTLVTLNVLSPIRISSELSKREDGSVQSTLANQFS 560
              .|...:..|.::||:             |||                    |.|
Mouse   378 VELPEASQAYKVDLCHF-------------STL--------------------GGV--------- 400

  Fly   561 PPLKSLLKQSITYGHFPLRGEPIANFNLDKSLNKIEIMKLEKMCLPRIISSFKFPSEFVEDQLTS 625
                                     ::||       :::|...|.|            |:..:..
Mouse   401 -------------------------YHLD-------VLELPPQCKP------------VKGWVLV 421

  Fly   626 EALKSRPNRLVKRLDTETAVEAKTPAEIYFEYESQERPERAFPIFEKTVAIEFSSAAELMPSIEC 690
            |.|:....|.:...||                ..:..|:..||..|.|:.|..|..
Mouse   422 EILQEGLQRFIYPPDT----------------TEEPDPDVTFPPIEVTLEIHKSVI--------- 461

  Fly   691 GNKATACGLLSTLEDIKEKYLQRPQELLDQIQVQVSKKSEKKAEKWENKNADGRSSAFSFRDRSS 755
                               :.:||                 :..:|:|:
Mouse   462 -------------------FFERP-----------------RVVRWDNE---------------- 474

  Fly   756 FANVNGKKTALDAKTKINETEIMITISTSENKMEIPSTSKTRTRRSGSVMKRRSTRKSARMEDMD 820
                 ||
Mouse   475 -----GK---------------------------------------------------------- 476

  Fly   821 RFRPMDSEPPVLLDHWTKEYIMESQINLETNTLTFRTDRLGIFGLAFKRYEHFPFRDWCLQPSED 885
                          .|..:.|.....|.|...|||..|.||...|....:.:.|::.|.:.|...
Mouse   477 --------------FWRSDGISSVYYNREDRLLTFSMDTLGPVTLIQDAHVNMPYQSWEMSPCGM 527

  Fly   886 NPDEVILSLDTFHVRMFFYI-------SARGVRGYVTDL-VKGYTAKPVKYLEIVEPISDFRELR 942
            |  :|:|.:.|..:.:..||       ::..:||...:. :||....|:.::
Mouse   528 N--KVLLIVKTVFMELQIYIKENLCMLASVKLRGKGLEFHLKGKWMAPIPFI------------- 577

  Fly   943 KLLIERNLNIFAENDASYYITNGYFSIKHIALELHTYNTMALQCKLMKFCRSSWNRLAQRRDIIV 1007
            ..|.|..||||....:.:|:.   .:.|...:||..|..|||......|..|.||.:.....:::
Mouse   578 LALKEAGLNIFPAVYSHFYVV---INNKVPQVELKAYRQMALLSSAFSFGWSKWNMVCNSTRVVI 639

  Fly  1008 EMK--IAKDNSDYSEVTMRITPEKTTFVKISEMCSDDVNVVKLRYEDTWRNVNNYNDFGQAIYSL 1070
            .::  ::::...::...:..:.::...:|:.|  .:|.....|| |.|        :|...:|.:
Mouse   640 RVREQLSEETEHHTWSLLMFSGDRAQMLKMQE--ENDKFSEALR-EGT--------EFHSTLYHM 693

  Fly  1071 -----NPHTLEGSNKDAMLFV----YLKRLLNEIRPLSYS 1101
                 :|..:|........|:    |   :|..||.||||
Mouse   694 MKDFASPVAMERVRHSNCQFIDSVCY---MLLSIRVLSYS 730

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33287	NP_001137993.1	Casc1_C	835..1053	CDD:432508	49/227 (22%)
Dnai7	NP_796196.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Casc1_N	39..229	CDD:464947	46/250 (18%)